Chloe Krakauer, PhD, MS
"I strive to use existing methods and develop novel approaches to extract unbiased information efficiently from electronic health data to increase health and wellness for all. I am particularly passionate about tailoring communication of quantitative results to intended audiences to encourage optimal decision-making."
Chloe Krakauer, PhD, MS
Senior Collaborative Biostatistician, Kaiser Permanente Washington Health Research Institute
Biography
Dr. Krakauer received her master’s degree in biostatistics from the University of Washington (UW) in 2014 and her doctorate in biostatistics from UW in 2021. Since 2021, Dr. Krakauer has worked as a collaborative biostatistician at KPWHRI.
Dr. Krakauer is currently a statistician with the Adult Changes in Thought (ACT) study, which aims to provide longitudinal data for the study of Alzheimer’s disease and related dementias and to identify Alzheimer’s risk factors. Dr. Krakauer has studied and continues to study multiple risk factors for Alzheimer’s and worsening cognition, including complications during pregnancy, eye health disparities, use of anticholinergics, and living arrangements.
Dr. Krakauer continues to contribute to analyses of clinical trials on addiction, including smoking cessation (ongoing GEMS clinical trial and prior pilot studies) and opioid cessation (the STRIPE study). Her scientific areas of particular interest include women’s health (pregnancy and peri/post-menopause) and treatment of weight and resulting bias in health care.
Her primary statistical methodological interest is in missing data. She continues to study optimal methods for addressing missing data through her dissertation work (focusing on regression with data missing not at random), research with the FDA Sentinel project, and methodological work using ACT Study data on addressing interval-censored covariates. Her additional area of particular methodological interest is quantitative communication and how it may better inform individual medical decision-making.
Research Interests and Experience
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Aging & Geriatrics
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Behavior Change
Dental care
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Biostatistics
Missing data, Bayesian statistics, decision theory, selection bias
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Chronic Illness Management
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Health Services & Economics
Quality of care at small practices
Recent Publications
Wartko PD, Krakauer C, Turner JA, Cook AJ, Boudreau DM, Sullivan MD STRategies to Improve Pain and Enjoy life (STRIPE): results of a pragmatic randomized trial of pain coping skills training and opioid medication taper guidance for patients on long-term opioid therapy 2023 Dec;164(12):2852-2864. doi: 10.1097/j.pain.0000000000002982. Epub 2023-08-25. PubMed
McClure JB, Heffner JL, Krakauer C, Mun S, Klasnja P, Catz SL Feasibility, Acceptability, and Potential Impact of a Novel mHealth App for Smokers Ambivalent About Quitting: Randomized Pilot Study 2023 Jun 28;11:e46155. doi: 10.2196/46155. Epub 2023-06-28. PubMed
Lee CS, Krakauer C, Su YR, Walker RL, Blazes M, McCurry SM, Bowen JD, McCormick WC, Lee AY, Boyko EJ, O'Hare AM, Larson EB, Crane PK Diabetic Retinopathy and Dementia Association, Beyond Diabetes Severity 2023 May;249:90-98. doi: 10.1016/j.ajo.2022.12.003. Epub 2022-12-10. PubMed
Hughes JP, Williamson BD, Krakauer C, Chau G, Ortiz B, Wakefield J, Hendrix C, Amico KR, Holtz TH, Bekker LG, Grant R Combining information to estimate adherence in studies of pre-exposure prophylaxis for HIV prevention: Application to HPTN 067 2022 Mar 15;41(6):1120-1136. doi: 10.1002/sim.9321. Epub 2022-01-25. PubMed
Coleman KF, Krakauer C, Anderson M, Michaels L, Dorr DA, Fagnan LJ, Hsu C, Parchman ML Improving Quality Improvement Capacity and Clinical Performance in Small Primary Care Practices 2021 Nov;19(6):499-506. doi: 10.1370/afm.2733. PubMed
Shores MM, Walsh TJ, Korpak A, Krakauer C, Forsberg CW, Fox AE, Moore KP, Heckbert SR, Thompson ML, Smith NL, Matsumoto AM Association Between Testosterone Treatment and Risk of Incident Cardiovascular Events Among US Male Veterans With Low Testosterone Levels and Multiple Medical Comorbidities 2021 Sep 7;10(17):e020562. doi: 10.1161/JAHA.120.020562. Epub 2021-08-21. PubMed
Krakauer C, Rice K. Chloe Krakauer and Kenneth Rice’s contribution to the discussion of ‘testing by betting: a strategy for statistical and scientific communication’ by Glenn Shafer. J R Stat Soc Series A. 2021;184:432-478. https://doi.org/10.1111/rssa.12660. PubMed
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Research
Digital tool could help people change smoking habits
A mobile application designed to engage smokers who are ambivalent about quitting shows promising results.
Research
Study evaluates biomarker criteria for Alzheimer’s risk
One-third of people classified as ‘highest risk’ may not develop Alzheimer’s disease, study suggests
Learn About the ACT Study
Understanding brain aging
For over 30 years, the Adult Changes in Thought (ACT) Study has been advancing our understanding of cognition, aging, and better ways to delay and prevent Alzheimer’s disease and related dementias.
Land Acknowledgment
Our Seattle offices sit on the occupied land of the Duwamish and by the shared waters of the Coast Salish people, who have been here thousands of years and remain. Learn about practicing land acknowledgment.