James D. Ralston, MD, MPH

Ralston_James_D_205x293.jpg

“My work focuses on helping patients who live with common chronic health conditions.”

James D. Ralston, MD, MPH

Senior Investigator, Kaiser Permanente Washington Health Research Institute
Physician, Washington Permanente Medical Group, Internal Medicine

Biography

James Ralston MD, MPH, is an internal medicine physician and senior investigator in health services and health informatics. His research mission is improving the health and care of patients living with common ongoing illnesses. His current areas of emphasis include understanding and honoring the priorities of patients living with multiple chronic conditions.

Dr. Ralston’s research focuses on developing and evaluating communication technologies that foster continuous care and a closer connection between patients and primary care teams. His commitment to finding effective ways to redesign care spans all stages of research, from project development to complete translation of results into clinical practice.

Examples of Dr. Ralston’s research projects include:

  • The Valuing Important Things in Active Lives (VITAL) study to improve care for people with multiple chronic conditions including diabetes, heart disease, and arthritis. VITAL uses participatory design methods with patients and providers to design and evaluate interactive care plans.
  • The Seeing Priorities study to build and test a single, trusted tool for individuals with multiple chronic conditions that illuminates connections between personal values and chronic illness management. The tool helps visualize, track, and share what matters most for self-management and care. 
  • Understanding and addressing differences in patient use of online health care services that could lead to care disparities.
  • Testing online care management of blood sugar control using an electronic health record shared with patients with type 2 diabetes. Control improved in patients receiving online care management in addition to usual care.
  • Validating and evaluating a clinical tool to identify patients with type 2 diabetes at risk of severe low blood sugar. This national collaboration uses Kaiser Permanente and Veterans Administration electronic health record data and machine learning methods.
  • Testing innovative engagement methods such as photos taken by study participants to document their values to ensure that patient priorities guide self-management plans and clinical care.
  • Working with primary care teams and clinics in rural and underserved areas to improve the care of their patients with chronic conditions.

Dr. Ralston is also a University of Washington affiliate professor in health services and biomedical informatics, where he serves on the committees of PhD and master’s degree students.

​​​​​​​

Research interests and experience

Recent publications

Lynch JA, Sharp RR, Aufox SA, Bland ST, Blout C, Bowen DJ, Buchanan AH, Halverson C, Harr M, Hebbring SJ, Henrikson N, Hoell C, Holm IA, Jarvik G, Kullo IJ, Kochan DC, Larson EB, Lazzeri A, Leppig KA, Madden J, Marasa M, Myers MF, Peterson J, Prows CA, Kulchak Rahm A, Ralston J, Milo Rasouly H, Scrol A, Smith ME, Sturm A, Stuttgen K, Wiesner G, Williams MS, Wynn J, Williams JL. Understanding the return of genomic sequencing results process: content review of participant summary letters in the eMERGE Research Network. J Pers Med. 2020;10(2):E38. doi: 10.3390/jpm10020038.  PubMed

Wiesner GL, Kulchak Rahm A, Appelbaum P, Aufox S, Bland ST, Blout CL, Christensen KD, Chung WK, Clayton EW, Green RC, Harr MH, Henrikson N, Hoell C, Holm IA, Jarvik GP, Kullo IJ, Lammers PE, Larson EB, Lindor NM, Marasa M, F Myers M, Peterson JF, Prows CA, Ralston JD, Milo Rasouly H, Sharp RR, Smith ME, Van Driest SL, Williams JL, Williams MS, Wynn J, Leppig KA. Returning results in the genomic era: initial experiences of the eMERGE Network. J Pers Med. 2020;10(2). pii: jpm10020030. doi: 10.3390/jpm10020030.  PubMed

Schuttner L, Coleman K, Ralston J, Parchman M. The role of organizational learning and resilience for change in building quality improvement capacity in primary care. Health Care Manage Rev. 2021;46(2):E1-E7. doi: 10.1097/HMR.0000000000000281. PubMed

Gordon AS, Rosenthal EA, Carrell DS, Amendola LM, Dorschner MO, Scrol A, Stanaway IB, DeVange S, Ralston JD, Zouk H, Rehm HL, Larson E, Crosslin DR, Leppig KA, Jarvik GP. Rates of actionable genetic findings in individuals with colorectal cancer or polyps ascertained from a community medical setting. Am J Hum Genet. 2019 Sep 5;105(3):526-533. doi: 10.1016/j.ajhg.2019.07.012. Epub 2019 Aug 15. PubMed

Hartzler AL, Ralston JD, Hannan TA, Kelleher KJ, Penfold RB. Designing safer use of antipsychotics among youths: a human-centered approach to an algorithm-based solution.  Psychiatr Serv. 2019 Jul 16:appips201800390. doi: 10.1176/appi.ps.201800390. [Epub ahead of print]. PubMed

Tchesnokova VL, Rechkina E, Chan D, Haile HG, Larson L, Ferrier K, Schroeder DW, Solyanik T, Shibuya S, Hansen K, Ralston JD, Riddell K, Scholes D, Sokurenko EV. Pandemic uropathogenic fluoroquinolone-resistant Escherichia coli have enhanced ability to persist in the gut and cause bacteriuria in healthy women. Clin Infect Dis. 2019 Jul 4. pii: ciz547. doi: 10.1093/cid/ciz547. [Epub ahead of print]. PubMed

Henrikson NB, Blasi PR, Corsmo JJ, Sheffer Serdoz E, Scrol A, Greene SM, Matthews TL, Ralston JD. "You really do have to know the local context": IRB administrators and researchers on the implications of the NIH Single IRB mandate for multisite genomic studies. J Empir Res Hum Res Ethics. 2019 Jul;14(3):286-295. doi: 10.1177/1556264619850440. Epub 2019 May 22. PubMed

Vizer LM, Eschler J, Koo BM, Ralston J, Pratt W, Munson S. "It's not just technology, it's people": constructing a conceptual model of shared health informatics for tracking in chronic illness management. J Med Internet Res. 2019 Apr 29;21(4):e10830. doi: 10.2196/10830. PubMed

Karter AJ, Warton EM, Moffet HH, Ralston JD, Huang ES, Miller DR, Lipska KJ. Revalidation of the hypoglycemia risk stratification tool using ICD-10 codes. Diabetes Care. 2019 Feb 14. pii: dc18-2154. doi: 10.2337/dc18-2154. [Epub ahead of print]. PubMed

O'Leary K, Tanghe D, Pratt W, Ralston J. Collaborative health reminders and notifications: insights from prototypes. AMIA Annu Symp Proc. 2018 Dec 5;2018:837-846. eCollection 2018. PubMed

 

News

E-STAR_Center_story_1col.jpg

Training scientists as partners in transforming primary care

Newly funded center will elevate equity and community in learning health system research.

Research

Resistent-E.-coli-rises_photo-Sokurenko-Lab_1col.jpg

Resistant E. coli rises despite drop in ciprofloxacin use

Community circulation of ciprofloxacin-resistant E. coli increased after 6-year reduction in antibiotic prescriptions

New findings

Adolescents-use-of-health-portal_1col.jpg

Some adolescents are more likely to use patient portal than others

A new study aims to understand trends in digital care communication among teens.

Open notes

African-American Doctor Working On Laptop

Concerns about note-sharing fade with practice

A new federal rule requiring physicians to give patients access to their notes may be easier to follow than physicians expected.

Research

CV-risk-calution-in-primary-care_screen_1col.jpg

CVD risk calculation: Can smaller clinics break through?

KPWHRI researchers uncover obstacles faced by smaller practices when adding CVD risk calculators into primary care.