Recent publications on Aging & Brain Health

Jackson ML, Walker R, Lee S, Larson E, Dublin S. Reply to: quality indicators of drug use and the risk of pneumonia in older adults without dementia. J Am Geriatr Soc. 2017 Feb 7. doi: 10.1111/jgs.14736. [Epub ahead of print]. PubMed

Larson EB. Dementia risk ticks up near major roadways. Alzforum, 2017. PubMed

Mez J, Marden JR, Mukherjee S, Walter S, Gibbons LE, Gross AL, Zahodne LB, Gilsanz P, Brewster P, Nho K, Crane PK, Larson EB, Glymour MM Alzheimer's disease genetic risk variants beyond APOE e4 predict mortality 2017 Jan;8:188-195. doi: 10.1016/j.dadm.2017.07.002. Epub 2017-08-14. PubMed

Bettcher BM, Ard MC, Reed BR, Benitez A, Simmons A, Larson EB, Sonnen JA, Montine TJ, Li G, Keene CD, Crane PK, Mungas D Association between Cholesterol Exposure and Neuropathological Findings: The ACT Study 2017 Jan;59(4):1307-1315. doi: 10.3233/JAD-161224. PubMed

Wang L, Hubbard RA, Walker RL, Lee EB, Larson EB, Crane PK Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease 2017 Jan;12(12):e0190107. doi: 10.1371/journal.pone.0190107. Epub 2017-12-22. PubMed

Dublin S, Walker RL, Gray SL, Hubbard RA, Anderson ML, Yu O, Montine TJ, Crane PK, Sonnen JA, Larson EB Use of Analgesics (Opioids and Nonsteroidal Anti-Inflammatory Drugs) and Dementia-Related Neuropathology in a Community-Based Autopsy Cohort 2017 Jan;58(2):435-448. doi: 10.3233/JAD-160374. PubMed

Bowles EJA, Walker RL, Anderson ML, Dublin S, Crane PK, Larson EB Risk of Alzheimer's disease or dementia following a cancer diagnosis 2017 Jan;12(6):e0179857. doi: 10.1371/journal.pone.0179857. Epub 2017-06-20. PubMed

Danila MI, Outman RC, Rahn EJ, Mudano AS, Thomas TF, Redden DT, Allison JJ, Anderson FA, Anderson JP, Cram PM, Curtis JR, Fraenkel L, Greenspan SL, LaCroix AZ, Majumdar SR, Miller MJ, Nieves JW, Safford MM, Silverman SL, Siris ES, Solomon DH, Warriner AH, Watts NB, Yood RA, Saag KG. A multi-modal intervention for Activating Patients at Risk for Osteoporosis (APROPOS): rationale, design, and uptake of online study intervention material. Contemp Clin Trials Commun. 2016;4:14-24.  PubMed

Langa KM, Larson EB, Crimmin EM, Faul JD, Levine DA, Kabeto MU, Weir DR. A comparison of the prevalence of dementia in the United States in 2000 and 2012. JAMA Intern Med. 2016 Nov 21. doi: 10.1001/jamainternmed.2016.6807. [Epub ahead of print]. PubMed

Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ; Alzheimer Disease Genetics Consortium., Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LA. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement. 2016 Oct 19. pii: S1552-5260(16)32931-4. doi: 10.1016/j.jalz.2016.09.002. [Epub ahead of print]. PubMed

Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, Ibrahim-Verbaas CA, Choi SH, Satizabal CL, Lopez OL, Beiser A, Ikram MA, Garcia ME, Hayward C, Varga TV, Ripatti S, Franks PW, Hallmans G, Rolandsson O, Jansson JH, Porteous DJ, Salomaa V, Eiriksdottir G, Rice KM, Bellen HJ, Levy D, Uitterlinden AG, Emilsson V, Rotter JI, Aspelund T; Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, Alzheimer’s Disease Genetic Consortium, Genetic and Environmental Risk in Alzheimer’s Disease consortium, O'Donnell CJ, Fitzpatrick AL, Launer LJ, Hofman A, Wang LS, Williams J, Schellenberg GD, Boerwinkle E, Psaty BM, Seshadri S, Shulman JM, Gudnason V, van Duijn CM. Rare functional variant in TM2D3 is associated with late-onset Alzheimer's disease. PLoS Genet. 2016 20;12(10):e1006327. doi: 10.1371/journal.pgen.1006327. eCollection 2016 Oct.  PubMed

Rundell SD, Goode AP, Suri P, Heagerty PJ, Comstock BA, Friedly JL, Gold LS, Bauer Z, Avins AL, Nedeljkovic SS, Nerenz DR, Kessler L, Jarvik JG. Effect of comorbid knee and hip osteoarthritis on longitudinal clinical and health care use outcomes in older adults with new visits for back pain.  Arch Phys Med Rehabil. 2017;98(1):43-50. doi: 10.1016/j.apmr.2016.06.022. Epub 2016 Aug 9.  PubMed

Greenwood-Hickman MA, Renz A, Rosenberg DE. Motivators and barriers to reducing sedentary behavior among overweight and obese older adults. Gerontologist. 2016 Aug;56(4):660-8. doi: 10.1093/geront/gnu163. Epub 2015 Feb 11. PubMed

Larson EB. Medical care when memory fails. JAMA Intern Med. 2016 Jul 25. doi: 10.1001/jamainternmed.2016.3566. [Epub ahead of print]. PubMed

Crane PK, Gibbons LE, Dams-O'Connor K, Trittschuh E, Leverenz JB, Keene CD, Sonnen J, Montine TJ, Bennett DA, Leurgans S, Schneider JA, Larson EB. Association of traumatic brain injury with late-life neurodegenerative conditions and neuropathologic findings. JAMA Neurol. 2016 Jul 11. doi: 10.1001/jamaneurol.2016.1948. [Epub ahead of print]. PubMed

Jackson ML, Walker R, Lee S, Larson E, Dublin S Predicting 2-Year Risk of Developing Pneumonia in Older Adults without Dementia 2016 Jul;64(7):1439-47. doi: 10.1111/jgs.14228. PubMed

Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams H, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF, Berr C, Amouyel P, Bennett DA, van Duijn C, DeStefano A, Launer L, Ikram MA, Crane PK, Lambert JC, Mayeux R, Seshadri S, for the International Genomics of Alzheimer’s Project. Evaluation of a genetic risk score to improve risk prediction for Alzheimer’s disease.  J Alzheimers Dis. 2016 Jun 18;53(3):921-32. doi: 10.3233/JAD-150749. PubMed

Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK; Alzheimer's Disease Genetics Consortium (ADGC). Assessment of the genetic variance of late-onset Alzheimer’s disease. Neurobiol Aging. 2016 May;41:200.e13-200.e20. doi: 10.1016/j.neurobiolaging.2016.02.024. Epub 2016 Mar 3. PubMed

Larson EB. Review: in older persons at vascular risk, statins do not prevent dementia or cognitive decline at 3.5 to 5 years. Ann Intern Med. 2016;164(8):JC42. doi: 10.7326/ACPJC-2016-164-8-042.  PubMed

Burke BT, Köttgen A, Law A, Grams M, Baer AN, Coresh J, McAdams-DeMarco MA. Gout in older adults: the Atherosclerosis Risk in Communities Study. J Gerontol A Biol Sci Med Sci. 2016 Apr;71(4):536-42. doi: 10.1093/gerona/glv120. Epub 2015 Dec 28. PubMed