Maricela Cruz, PhD

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“Developing flexible yet pragmatic and robust statistical methodology that can accommodate the intricacies of real-world circumstances is paramount in addressing public health concerns.”

Maricela Cruz, PhD

Associate Biostatistics Investigator, Kaiser Permanente Washington Health Research Institute
Affiliate Assistant Professor of Biostatistics, University of Washington

Biography

Maricela Cruz, PhD, is a biostatistician passionate about conducting public health research with a specific focus on improving the health of disenfranchised communities.

Dr. Cruz’s research centers on developing flexible and robust statistical methods to evaluate health care interventions, particularly using electronic health records, to inform clinical and public health practices. She specializes in analytic methods for pre-post longitudinal correlated data, including interrupted time series (ITS), time series analysis, longitudinal data, change-point detection, and difference-in-differences. Dr. Cruz additionally has experience in developing and evaluating prediction models. The pre-post methods she develops allow health systems to evaluate interventions over time, while her prediction model work helps identify at-risk encounters — both are critical in shaping effective health practices.

Dr. Cruz has developed and evaluated several ITS models to estimate the impact of new nursing structures (and similar health care interventions) on patient experience outcomes in the presence of potentially lagged (or anticipatory) treatment effects. To communicate and encourage access to her methods in the broader public health community, Dr. Cruz co-created the Robust Interrupted Time Series toolbox (https://biostatistics-kaust.github.io/robust_time_series_toolbox/), a stand-alone, user-friendly application implementing the Robust Multiple ITS model that Dr. Cruz developed in 2019 for single and multiple ITS.

Dr. Cruz provides statistical and scientific leadership in collaborative public health and health care delivery projects aimed at improving health outcomes for disenfranchised communities. She collaborates on several projects aiming to improve care for people with a history of suicide ideation and on projects designing and evaluating health care interventions, such as value-based drug formularies and clinical decision support systems for at-risk encounters.

Dr. Cruz obtained her PhD in statistics from the University of California Irvine in 2019. She is an affiliate assistant professor in biostatistics at the University of Washington.

Recent Publications

Lozano PM, Bobb JF, Kapos FP, Cruz M, Mooney SJ, Hurvitz PM, Anau J, Theis MK, Cook A, Moudon AV, Arterburn DE, Drewnowski A Residential Density Is Associated With BMI Trajectories in Children and Adolescents: Findings From the Moving to Health Study 2024 Jun;3(3):100225. doi: 10.1016/j.focus.2024.100225. Epub 2024-03-15. PubMed

Simon GE, Cruz M, Boggs JM, Beck A, Shortreed SM, Coley RY Predicting Outcomes of Antidepressant Treatment in Community Practice Settings 2024 May;75(5):419-426. doi: 10.1176/appi.ps.20230380. Epub 2023-12-05. PubMed

Cruz M, Wei A, Hardin J, Radunskaya A. Long-term averages of the stochastic logistic map. J Differ Equ Appl.1-29. https://doi.org/10.1080/10236198.2024.2316379. PubMed

Rosenberg DE, Cruz MF, Mooney SJ, Bobb JF, Drewnowski A, Moudon AV, Cook AJ, Hurvitz PM, Lozano P, Anau J, Theis MK, Arterburn DE Neighborhood built and food environment in relation to glycemic control in people with type 2 diabetes in the moving to health study 2024 Mar;86:103216. doi: 10.1016/j.healthplace.2024.103216. Epub 2024-02-23. PubMed

Simon GE, Cruz M, Shortreed SM, Sterling SA, Coleman KJ, Ahmedani BK, Yaseen ZS, Mosholder AD Stability of Suicide Risk Prediction Models During Changes in Health Care Delivery 2024 Feb;75(2):139-147. doi: 10.1176/appi.ps.20230172. Epub 2023-08-17. PubMed

 

Research

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Suicide attempts decreased after adding suicide care to primary care

Safety planning and risk screening improved outcomes for adult patients.

Research

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Neighborhood density connected to changes in body mass index for children

Study uses geographic data to track change over time.

KPWHRI in the media

Addressing structural racism in clinical prediction models

How structural racism is impacting clinical prediction models

JSM TV, Aug. 6, 2024