Aruna Kamineni, PhD, MPH, came to Kaiser Permanente Washington Health Research Institute in 2009 with a wealth of experience in chronic disease epidemiology. Dr. Kamineni has expertise in using case-control methods to evaluate screening efficacy, and her research focuses on addressing evidence gaps for clinical guidelines, particularly for cervical and colorectal cancer prevention. A substantial portion of her work has focused on developing infrastructure and methods for research using electronic clinical and administrative health care data.
Since 2011, Dr. Kamineni has participated in the National Cancer Institute’s Population-based Research to Optimize the Screening Process (PROSPR) consortium to evaluate and improve cancer screening in U.S. community settings. As a principal investigator for multisite cervical and colorectal cancer PROSPR Research Centers, Dr. Kamineni is leading and collaborating on work to determine how to optimally use screening tests and consider how to tailor screening for population subgroups.
Dr. Kamineni’s research goals include studying the impact of human papillomavirus (HPV) DNA testing and HPV vaccination on cervical cancer and screening programs. Multidisciplinary collaboration is a valued and important driver of Dr. Kamineni’s research and she embraces a team science approach to optimizing cancer prevention.
Cervical cancer; colorectal cancer; screening; disparities
Electronic clinical and administrative data infrastructure development for research; case-control studies; team science
Burnett-Hartman AN, Chubak J, Hua X, Ziebell R, Kamineni A, Zhu LC, Upton MP, Malen RC, Hardikar S, Newcomb PA The association between colorectal sessile serrated adenomas/polyps and subsequent advanced colorectal neoplasia 2019 Sep;30(9):979-987. doi: 10.1007/s10552-019-01205-y. Epub 2019-07-09. PubMed
Burnett-Hartman AN, Kamineni A, Corley DA, Singal AG, Halm EA, Rutter CM, Chubak J, Lee JK, Doubeni CA, Inadomi JM, Doria-Rose VP, Zheng Y Colonoscopy Indication Algorithm Performance Across Diverse Health Care Systems in the PROSPR Consortium 2019 Aug 2;7(1):37. doi: 10.5334/egems.296. Epub 2019-08-02. PubMed
Ko CW, Doria-Rose VP, Barrett MJ, Kamineni A, Enewold L, Weiss NS Screening flexible sigmoidoscopy versus colonoscopy for reduction of colorectal cancer mortality 2019 Jul;34(7):1273-1281. doi: 10.1007/s00384-019-03300-7. Epub 2019-05-31. PubMed
Doria-Rose VP, Kamineni A, Barrett MJ, Ko CW, Weiss NS Case-Control Studies of the Efficacy of Screening Tests That Seek to Prevent Cancer Incidence: Results of an Approach That Utilizes Administrative Claims Data That Do Not Provide Information Regarding Test Indication 2019 Apr;188(4):703-708. doi: 10.1093/aje/kwy274. PubMed
Kamineni A, Tiro JA, Beaber EF, Silverberg MJ, Wheeler CM, Chao CR, Chubak J, Skinner CS, Corley DA, Kim JJ, Balasubramanian BA, Paul Doria-Rose V, PROSPR consortium Cervical Cancer Screening Research in the PROSPR I Consortium: Rationale, Methods, and Baseline Findings from a U.S. Cohort 2019 Mar 15;144(6):1460-1473. doi: 10.1002/ijc.31940. Epub 2018-12-20. PubMed
Ko CW, Doria-Rose VP, Barrett MJ, Kamineni A, Enewold L, Weiss NS Screening colonoscopy and flexible sigmoidoscopy for reduction of colorectal cancer incidence: A case-control study 2019 Jan;14(12):e0226027. doi: 10.1371/journal.pone.0226027. Epub 2019-12-05. PubMed
Selby K, Jensen CD, Lee JK, Doubeni CA, Schottinger JE, Zhao WK, Chubak J, Halm E, Ghai NR, Contreras R, Skinner C, Kamineni A, Levin TR, Corley DA Influence of Varying Quantitative Fecal Immunochemical Test Positivity Thresholds on Colorectal Cancer Detection: A Community-Based Cohort Study 2018 Nov;169(7):439-447. doi: 10.7326/M18-0244. Epub 2018-09-18. PubMed
Singal AG, Corley DA, Kamineni A, Garcia M, Zheng Y, Doria-Rose PV, Quinn VP, Jensen CD, Chubak J, Tiro J, Doubeni CA, Ghai NR, Skinner CS, Wernli K, Halm EA Patterns and predictors or repeat fecal immunochemical and occult blood test screening in four large health care systems in the United States 2018 May;113(5):746-754. doi: 10.1038/s41395-018-0023-x. Epub 2018-02-27. PubMed
Hubbard RA, Johnson E, Chubak J, Wernli KJ, Kamineni A, Bogart A, Rutter CM Accounting for misclassification in electronic health records-derived exposures using generalized linear finite mixture models 2017 Jun;17(2):101-112. doi: 10.1007/s10742-016-0149-5. Epub 2016-06-03. PubMed
Balasubramanian BA, Garcia MP, Corley DA, Doubeni CA, Haas JS, Kamineni A, Quinn VP, Wernli K, Zheng Y, Skinner CS. Racial/ethnic differences in obesity and comorbidities between safety-net- and non safety-net integrated health systems. Medicine (Baltimore). 2017;96(11):e6326. doi: 10.1097/MD.0000000000006326. PubMed
How KPWHRI is contributing to better cancer screening and better outcomes for patients.
Aruna Kamineni, PhD, MPH, discusses her recent study on how guidelines report screening risks.
Research informs care as Kaiser Permanente Washington, exceeding 80 percent screening rate, launches home-based 'FIT First' pilot.
Managed Healthcare Executive, Dec. 8, 2022