Aruna Kamineni, PhD, MPH, came to Kaiser Permanente Washington Health Research Institute in 2009 with a wealth of experience in chronic disease epidemiology. Dr. Kamineni has expertise in using case-control methods to evaluate screening efficacy, and her research focuses on addressing evidence gaps for clinical guidelines, particularly for cervical and colorectal cancer prevention. A substantial portion of her work has focused on developing infrastructure and methods for research using electronic clinical and administrative health care data.
Since 2011, Dr. Kamineni has participated in the National Cancer Institute’s Population-based Research to Optimize the Screening Process (PROSPR) consortium to evaluate and improve cancer screening in U.S. community settings. As a principal investigator for multisite cervical and colorectal cancer PROSPR Research Centers, Dr. Kamineni is leading and collaborating on work to determine how to optimally use screening tests and consider how to tailor screening for population subgroups.
Dr. Kamineni’s research goals include studying the impact of human papillomavirus (HPV) DNA testing and HPV vaccination on cervical cancer and screening programs. Multidisciplinary collaboration is a valued and important driver of Dr. Kamineni’s research and she embraces a team science approach to optimizing cancer prevention.
Cervical cancer; colorectal cancer; screening; disparities
Electronic clinical and administrative data infrastructure development for research; case-control studies; team science
Chubak J, Kamineni A, Buist DSM, Anderson ML, Whitlock EP. Aspirin use for the prevention of colorectal cancer: an updated systematic evidence review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US); 2015 Sep. Report No.: 15-05228-EF-1. U.S. Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews. PubMed
Weinmann S, Williams AE, Kamineni A, Buist DS, Masterson EE, Stout NK, Stark A, Ross TR, Owens CL, Field TS, Doubeni CA. Cervical cancer screening and follow-up in 4 geographically diverse US health care systems, 1998 through 2007. Cancer. 2015 Sep 1;121(17):2976-83. doi: 10.1002/cncr.29445. Epub 2015 May 18. PubMed
Beaber EF, Kim JJ, Schapira MM, Tosteson AN, Zauber AG, Geiger AM, Kamineni A, Weaver DL, Tiro JA. Unifying screening processes within the PROSPR consortium: a conceptual model for breast, cervical, and colorectal cancer screening. J Natl Cancer Inst. 2015 May 7;107(6). pii: djv120. doi: 10.1093/jnci/djv120. Print 2015. PubMed
Chubak J, Hubbard RA, Johnson E, Kamineni A, Rutter CM. Assessing the effectiveness of a cancer screening test in the presence of another screening modality. J Med Screen. 2015 Jun;22(2):69-75. doi: 10.1177/0969141314562036. Epub 2014 Dec 9. PubMed
Chubak J, Hubbard RA, Johnson E, Kamineni A, Rutter CM. Assessing the effectiveness of a screening test for cancer in the presence of another screening modality in nonrandomized studies J Med Screen. 2015 Jun;22(2):69-75. doi: 10.1177/0969141314562036. Epub 2014 Dec 9. PubMed
Adams KF, Johnson EA, Chubak J, Kamineni A, Doubeni CA, Buist DS, Williams AE, Weinmann S, Doria-Rose VP, Rutter CM. Development of an algorithm to classify colonoscopy indication from coded health care data. EGEMS. (Wash DC). 2015 May 18;3(1):1171. doi: 10.13063/2327-9214.1171. eCollection 2015. PubMed
Rutter CM, Greenlee RT, Johnson E, Stark A, Weinmann S, Kamineni A, Adams K, Doubeni CA. Prevalence of colonoscopy before age 50. Prev Med. 2015 Jan 4. pii: S0091-7435(14)00510-6. doi: 10.1016/j.ypmed.2014.12.028 [Epub ahead of print]. PubMed
Arem H, Yu K, Xiong X, Moy K, Freedman ND, Mayne ST, Albanes D, Arslan AA, Austin M, Bamlet WR, Beane-Freeman L, Bracci P, Canzian F, Cotterchio M, Duell EJ, Gallinger S, Giles GG, Goggins M, Goodman PJ, Hartge P, Hassan M, Helzlsouer K, Henderson B, Holly EA, Hoover R, Jacobs EJ, Kamineni A, Klein A, Klein E, Kolonel LN, Li D, Malats N, Männistö S, McCullough ML, Olson SH, Orlow I, Peters U, Petersen GM, Porta M, Severi G, Shu XO, Visvanathan K, White E, Yu H, Zeleniuch-Jacquotte A, Zheng W, Tobias GS, Maeder D, Brotzman M, Risch H, Sampson JN, Stolzenberg-Solomon RZ. Vitamin D metabolic pathway genes and pancreatic cancer risk. PLoS One. 2015 Mar 23;10(3):e0117574. doi: 10.1371/journal.pone.0117574. eCollection 2015. PubMed
Owens CL, Buist DS, Peterson D, Kamineni A, Weinmann S, Ross T, Williams AE, Stark A, Adams KF, Doubeni CA, Field TS. Follow-up and clinical significance of unsatisfactory liquid-based Papanicolaou tests. Cancer Cytopathol. 2015 Jan;123(1):59-65. doi: 10.1002/cncy.21490. Epub 2014 Oct 23. PubMed
Arem H, Yu K, Xiong X, Moy K, Freedman ND, Mayne ST, Albanes D, Arslan AA, Austin M, Bamlet WR, Beane-Freeman L, Bracci P, Canzian F, Cotterchio M, Duell EJ, Gallinger S, Giles GG, Goggins M, Goodman PJ, Hartge P, Hassan M, Helzlsouer K, Henderson B, Holly EA, Hoover R, Jacobs EJ, Kamineni A, Klein A, Klein E, Kolonel LN, Li D, Malats N, Männistö S, McCullough ML, Olson SH, Orlow I, Peters U, Petersen GM, Porta M, Severi G, Shu XO, Visvanathan K, White E, Yu H, Zeleniuch-Jacquotte A, Zheng W, Tobias GS, Maeder D, Brotzman M, Risch H, Sampson JN, Stolzenberg-Solomon RZ. Correction: Vitamin D metabolic pathway genes and pancreatic cancer risk. PLoS One. 2015 Jun 3;10(6):e0129983. doi: 10.1371/journal.pone.0129983. eCollection 2015. PubMed
How KPWHRI is contributing to better cancer screening and better outcomes for patients.
Aruna Kamineni, PhD, MPH, discusses her recent study on how guidelines report screening risks.
Research informs care as Kaiser Permanente Washington, exceeding 80 percent screening rate, launches home-based 'FIT First' pilot.
Managed Healthcare Executive, Dec. 8, 2022