Laura B. Harrington, PhD, MPH, is a cardiovascular epidemiologist and Assistant Investigator at Kaiser Permanente Washington Health Research Institute (KPWHRI) who works to improve the understanding of cardiovascular event risk in relation to a variety of risk factors, with a focus on modifiable factors. In particular, her research focuses on cardiovascular risk among older women and on risk factors associated with incident and recurrent venous thromboembolism (VTE), blood clots occurring predominantly in the veins of the legs or lungs.
VTE is the third most common cardiovascular diagnosis in the United States, yet there is more to understand about its etiology and prevention. Thus, Dr. Harrington’s work currently aims to improve health by furthering our knowledge of the etiology, prevention, and treatment of these events.
In August 2018, Dr. Harrington joined KPWHRI, where she is leading research as part of a career development award from the National Heart, Lung, and Blood Institute to evaluate the relationship between physical activity, sedentary behavior, and VTE risk. She is using data from the Women’s Health Initiative, the Nurses’ Health Study, and interview data collected directly from KP Washington enrollees, as part of the Research about Venous Events (RaVE) study, to improve the understanding of how physical activity and sedentary behavior are associated with the risk of a first VTE, as well as health after someone has experienced a VTE.
Before joining KPWHRI, Dr. Harrington completed a postdoctoral fellowship in cardiovascular epidemiology in the Harvard T.H. Chan School of Public Health’s Department of Nutrition, a PhD in epidemiology at the University of Washington, and an MPH in epidemiology at the University of Michigan. She conducts epidemiologic research using a variety of data sources, including the integrated health care delivery system-based Heart and Vascular Health Study, the Women’s Health Initiative, the Cardiovascular Health Study, the Nurses’ Health Studies I and II, the Health Professionals Follow-up Study, and the Adult Changes in Thought Study.
Dr. Harrington is also an Affiliate Assistant Professor in the Department of Epidemiology at the University of Washington, where she enjoys guest lecturing and mentoring students.
Risk factors for incident and recurrent venous thrombosis; pharmacologic risk factors; lifestyle-based risk factors; hormonally-related risk factors; women’s cardiovascular health
Endogenous hormones and exogenous hormone use in relation to cardiovascular health; menopausal transition; vasomotor symptoms
Long-term prognosis following cardiovascular events
Pharmacologic risk factors associated with cardiovascular outcomes
Greenwood-Hickman MA, Shapiro LN, Chen S, Crane PK, Harrington LB, Johnson K, LaCroix AZ, Lane LG, McCurry SM, Shaw PA, Rosenberg DE. Understanding resilience: Lifestyle-based behavioral predictors of mental health and well-being in community-dwelling older adults during the COVID-19 pandemic. BMC Geriatr. 2024;24(1):676. doi: 10.1186/s12877-024-05251-3. PubMed
Harrington LB, Benz L, Haneuse S, Johnson E, Coleman KJ, Courcoulas AP, Li RA, Theis MK, Cooper J, Chin PL, Grinberg GG, Daigle CR, Chang JH, Um SS, Yenumula PR, Getty JZ, Arterburn DE. Bariatric Surgery and the Long-Term Risk of Venous Thromboembolism: A Population-Based Cohort Study. Obes Surg. 2024;34(6):2017-2025. doi: 10.1007/s11695-024-07236-y. Epub 2024 Apr 30. PubMed
Harrington LB, Powers JD, Bayliss EA, Fortmann SP, Shortreed SM, Walker RL, Floyd JS, Kuntz J, Fuller S, Albertson-Junkans L, Lee MH, Temposky LA, Dublin S. Current use of estrogen-containing oral contraceptives or hormone therapy and risk of COVID-19 infection and hospitalization: A population-based cohort study. Am J Epidemiol. 2024 May 16:kwae066. doi: 10.1093/aje/kwae066. [Epub ahead of print]. PubMed
Harrington LB, Ehlert AN, Thacker EL, Jenny NS, Lopez O, Cushman M, Olson NC, Fitzpatrick A, Mukamal KJ, Jensen MK. Levels of procoagulant factors and peak thrombin generation in relation to dementia risk in older adults: The Cardiovascular Health Study. Thromb Res. 2024;235:148-154. doi: 10.1016/j.thromres.2024.01.024. Epub 2024 Feb 4. PubMed
Floyd JS, Walker RL, Kuntz JL, Shortreed SM, Fortmann SP, Bayliss EA, Harrington LB, Fuller S, Albertson-Junkans LH, Powers JD, Lee MH, Temposky LA, Dublin S. Association between diabetes severity and risks of COVID-19 infection and outcomes. J Gen Intern Med.2023 May;38(6):1484-1492. doi: 10.1007/s11606-023-08076-9. Epub 2023 Feb 16. PubMed
Oral contraceptives, hormone therapy not linked to more severe COVID outcomes.
Largest study to date helps patients weigh risks and benefits of surgery.
Epidemiologist Laura B. Harrington, PhD, MPH, speaks about working in cardiovascular and aging research.
Dr. Sascha Dublin tells how studies of KP electronic health record data can improve COVID-19 treatment and prevention.