Medical anthropologist Clarissa Hsu, PhD, has been doing Kaiser Permanente research since 2001, and became an official member of the faculty in 2011. She conducts research using a holistic approach that unites the cultural, social, and political factors that shape health and health care. Dr. Hsu was one of the first researchers to receive funding from the national Patient-Centered Outcomes Research Institute (PCORI), which supports studies on issues that are a high priority for patients, caregivers, and clinicians. PCORI-funded research follows an innovative model, including patient input at all steps in the research process. Dr. Hsu and her team christened her PCORI project LINCC: Learning to Integrate Neighborhoods and Clinical Care.
The LINCC project designed, piloted, and evaluated a new primary care role: connecting patients to community resources. This new community resource specialist role was spread throughout Kaiser Permanente Washington, with a robust evaluation and implementation support co-led by Dr. Hsu through KPWHRI’s Center for Accelerating Care Transformation. LINCC also resulted in the creation of valuable health care resources, including an article on having patients as co-investigators, as well as a guide and set of care-design templates for engaging a cohort of patients in co-designing care.
Dr. Hsu is also at the forefront of other prevalent health issues, working to document, design, evaluate, and disseminate new approaches and best practices. She seeks to help chronic pain patients taper off and find alternatives to opioids. She also works to improve how care delivery systems interact with patients and family members around sensitive and complex topics such as dementia diagnoses, use of antipsychotics in youth, blood pressure diagnosis and control, cannabis use, and childhood vaccinations.
Dr. Hsu is an affiliate professor at the University of Washington School of Public Health.
Patient experiences with complementary and alternative medicine
Clinic-community linkages; preventive medicine; addressing social determinants of health
Prevention and treatment
Hansel L, Hsu C, Munson S, Thompson M, Ehrlich K, Hall Y, Anderson M, Evers S, Marcus-Smith M, McClure J, Green BB. Patient experiences with blood pressure measurement for hypertension diagnosis. Am J Hypertens. 2024 Jul 12:hpae088. doi: 10.1093/ajh/hpae088. Online ahead of print. PubMed
Hsu C, Mogk J, Hansell L, Glass JE, Allen C. Rapid Group Analysis Process (Rap-GAP): A novel approach to expedite qualitative health research data analysis. Int J Qual Methods. 2024 May 24. https://doi.org/10.1177/16094069241256275. PubMed
Hall YN, Anderson ML, McClure JB, Ehrlich K, Hansell LD, Hsu CW, Margolis KL, Munson SA, Thompson MJ, Green BB. Relationship of blood pressure, health behaviors, and new diagnosis and control of hypertension in the BP-CHECK Study. Circ Cardiovasc Qual Outcomes. 2024;17(2):e010119. doi: 10.1161/CIRCOUTCOMES.123.010119. Epub 2024 Feb 8. PubMed
Ralston JD, Anderson M, Ng J, Bashir A, Ehrlich K, Burns-Hunt D, Cotton M, Hansell L, Hsu C, Hunt H, Karter AJ, Levy SM, Ludman E, Madziwa L, Omura EM, Rogers K, Sevey B, Shaw JAM, Shortreed SM, Singh U, Speight J, Sweeny A, Tschernisch K, Sergei Tschernisch S, Yarborough L. Preventing severe hypoglycemia in adults with type 2 diabetes (PHT2): Design, delivery and evaluation framework for a randomized controlled trial. Contemp Clin Trials. 2024 Jan 20;139:107456. doi: 10.1016/j.cct.2024.107456. [Epub ahead of print]. PubMed
Hsu C, Williamson BD, Becker M, Berry B, Cook AJ, Derus A, Estrada C, Gacuiri M, Kone A, McCracken C, McDonald B, Piccorelli AV, Senturia K, Volney J, Wilson KB, Green BB. Engaging staff to improve COVID-19 vaccination response at long-term care facilities (ENSPIRE): A cluster randomized trial of co-designed, tailored vaccine promotion materials. Contemp Clin Trials. 2023 Dec 3;136:107403. doi: 10.1016/j.cct.2023.107403. [Epub ahead of print]. PubMed
Dublin S, Greenwood-Hickman MA, Karliner L, Hsu C, Coley RY, Colemon L, Carrasco A, King D, Grace A, Lee SJ, Walsh JME, Barrett T, Broussard J, Singh U, Idu A, Yaffe K, Boustani M, Barnes DE. The electronic health record Risk of Alzheimer's and Dementia Assessment Rule (eRADAR) Brain Health Trial: Protocol for an embedded, pragmatic clinical trial of a low-cost dementia detection algorithm. Contemp Clin Trials. 2023;135:107356. doi: 10.1016/j.cct.2023.107356. Epub 2023 Oct 17. PubMed
Williamson BD, Coley RY, Hsu C, McCracken CE, Cook AJ. Considerations for subgroup analyses in cluster-randomized trials based on aggregated individual-level predictors. Prev Sci. 2023 Oct 28. doi: 10.1007/s11121-023-01606-1. [Epub ahead of print]. PubMed
Green BB, Anderson ML, Ehrlich K, Hall YN, Hansell LD, Hsu C, Margolis KL, McClure JB, Munson S, Thompson MJ. Is hypertension diagnostic testing and diagnosis associated with psychological distress? Am J Hypertens. 2023 Sep 9:hpad083. doi: 10.1093/ajh/hpad083. Online ahead of print. PubMed
Casey Lion K, Arthur KC, García MF, Hsu C, Sotelo Guerra LJ, Chisholm H, Griego E, Ebel BE, Penfold RB, Rafton S, Zhou C, Mangione-Smith R. Pilot evaluation of the Family Bridge Program, a communication- and culture-focused inpatient patient navigation program. Acad Pediatr. 2024 Jan-Feb;24(1):33-42. doi: 10.1016/j.acap.2023.06.021. Epub 2023 Jun 22. PubMed
Mogk JM, Matson TE, Caldeiro RM, Garza Mcwethy AM, Beatty T, Sevey BC, Hsu CW, Glass JE. Implementation and workflow strategies for integrating digital therapeutics for alcohol use disorders into primary care: A qualitative study. Addict Sci Clin Pract. 2023;18(1):27. doi: 10.1186/s13722-023-00387-w. PubMed
Use in pregnancy and screening in primary care studied by KPWHRI’s Kiel, Matson, and Lapham.
Study ends but benefits for Kaiser Permanente members continue — thanks to a new support role in the regions’ clinics, writes Dr. Clarissa Hsu.
Partnering with Patients as Equals in Co-Designing Primary Care: Examples and Tools from the LINCC Project
Clarissa Hsu, PhD, asked parents why they decline or delay vaccinating their children to explore ways to overcome barriers to getting vaccinated.
The Patient-Centered Outcomes Research Institute plans to award $4.75 million to compare ways to raise COVID-19 immunization rates.
Healthcare Innovation, July 25, 2022