Recent publications on Aging & Geriatrics

Zhang B, McEvoy LK, Nguyen S, Espeland MA, Rapp SR, Horvath S, Lu AT, LaCroix AZ, Nievergelt CM, Maihofer AX, Resnick SM, Mielke MM, Beckman K, Li D, Silver B, Manson JE, Ferrucci L, Shadyab AH Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease 2025 Dec;21(12):e70983. doi: 10.1002/alz.70983. PubMed

Florez-Acevedo S, Greenwood-Hickman MA, Zhu W, Cook AJ, Delaney K, Green BB, Arterburn DE, McClure JB, Rosenberg DE Exploratory Analysis of Mental Health and Quality of Life Outcomes in a Randomized Controlled Trial to Reduce Sitting Time in Older Adults With Obesity 2025 Nov 12 doi: 10.1123/japa.2024-0387. Epub 2025-11-12. PubMed

Godrich D, Pasteris J, Martin ER, Kunkle B, Naj AC, Hamilton K, Wang H, Lee WP, Dumitrescu L, Hohman TJ, Mayeux R, Larson EB, Crane PK, Keene CD, Latimer C, Mukherjee S, Kofler J, Kamboh MI, Bennett DA, Molina-Porcel L, Schellenberg G, Pericak-Vance MA, Cuccaro M, Scott WK, Rundek T, Kukull W, Montine T, Beecham GW, Alzheimer's Disease Genetics Consortium (ADGC) Genome-wide association studies of TDP-43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B 2025 Nov;21(11):e70760. doi: 10.1002/alz.70760. PubMed

Phelan EA, Balderson BH, Fujii MM, Graham VF, Theis MK, Gray SL Deprescribing Central Nervous System-Active Medications Among Community-Dwelling Older Adults with Dementia in Primary Care: A Feasibility Study 2025 Oct 22;22(11). doi: 10.3390/ijerph22111611. Epub 2025-10-22. PubMed

Levoy K, Torke AM, Longtin K, Matthias MS, Hickman SE. A pilot study of a primary palliative care communication intervention (precursor) to address supportive oncology needs for patients with incurable cancer and their caregivers in the outpatient oncology setting. Cancer Control. 2025 Jan-Dec;32:10732748251390952. doi: 10.1177/10732748251390952. Epub 2025 Oct 17. PubMed

Ferrante GR, Kahn J, McCurry SM, Vitiello MV, Von Korff M, de la Iglesia HO Lunar rhythmicity in the actigraphic sleep patterns of older adults with chronic pain and sleep disturbances is associated with the severity of their self-reported sleep disturbance 2025 Oct 13 doi: 10.1093/sleep/zsaf230. Epub 2025-08-11. PubMed

Nguyen S, Lu A, Horvath S, Espeland MA, Rapp SR, Maihofer AX, Nievergelt CM, LaCroix AZ, McEvoy LK, Resnick SM, Beckman K, Shadyab AH Epigenetic clocks of biological aging and risk of incident mild cognitive impairment and dementia: the Women's Health Initiative Memory Study 2025 Oct doi: 10.1101/2025.09.29.25336927. Epub 2025-10-01. PubMed

Lee CS, Su YR, Walker RL, Krakauer C, Blazes M, Johnson EA, Cronkite D, Bowers W, Hess C, Arterburn D, Agrón E, Chew EY, Crane PK A Novel AMD Severity Scoring System Leveraging the AREDS Studies and Routine Clinical Electronic Medical Records 2025 Oct;132(10):1076-1087. doi: 10.1016/j.ophtha.2025.04.026. Epub 2025-04-29. PubMed

Doubleday A, Blanco M, Adar SD, Hajat A, Li G, Larson EB, Crane PK, Sheppard L Traffic-related air pollutant exposure and physical performance in the Adult Changes in Thought cohort 2025 Oct;204:109850. doi: 10.1016/j.envint.2025.109850. Epub 2025-10-10. PubMed

Harrington LB, Tom SE, Krakauer C, Wartko PD, Chau K, Muiruri R, Micks E, McEvoy LK, LaCroix AZ, Miller EC Adverse Pregnancy Outcomes and Cognitive Change in Older Women 2025 Sep 29 doi: 10.1177/15409996251383009. Epub 2025-09-29. PubMed

Krueger E, Mosher CE, Lewson A, Hickman SE, Wu W, Prigerson HG. Cancer prognostic awareness: Relations to patient and caregiver quality of life and care preferences J Pain Symptom Manage. 2025 Sep;70(3):313-323.e3. doi: 10.1016/j.jpainsymman.2025.06.002. Epub 2025 Jun 10. PubMed

Hartman SJ, LaCroix AZ, Sears DD, Natarajan L, Zablocki RW, Chen R, Patterson JS, Dillon L, Sallis JF, Schenk S, Dunstan DW, Owen N, Rosenberg DE Impacts of Reducing Sitting Time or Increasing Sit-to-Stand Transitions on Blood Pressure and Glucose Regulation in Postmenopausal Women: Three-Arm Randomized Controlled Trial 2025 Aug 26;152(8):492-504. doi: 10.1161/CIRCULATIONAHA.124.073385. Epub 2025-07-25. PubMed

Zhang B, McEvoy LK, Nguyen S, Espeland MA, Rapp SR, Horvath S, Lu A, LaCroix AZ, Nievergelt CM, Maihofer AX, Resnick SM, Mielke MM, Beckman K, Li D, Silver B, Manson JE, Ferrucci L, Shadyab AH Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease 2025 Aug 14 doi: 10.1101/2025.08.12.25333453. Epub 2025-08-14. PubMed

Snyder LB, Newton KM, Ng HX, Reed SD, Guthrie KA, Zambrano V, LaCroix AZ Positive impact of a menopause website - MyMenoplan.org - on treatment intentions, knowledge, and decision making: A randomized controlled trial 2025 Aug;199:108630. doi: 10.1016/j.maturitas.2025.108630. Epub 2025-06-05. PubMed

Phillips JM, Dumitrescu LC, Archer DB, Regelson AN, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Kukull WA, Biber S, Mez J, Mahoney ER, Clifton M, Libby JB, Walters S, Bush WS, Engelman CD, Lu Q, Fardo DW, Widaman KF, Buckley RF, Mormino EC, Sanders RE, Clark LR, Gifford KA, Vardarajan B, Cuccaro ML, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Haines JL, Jefferson AL, Johnson SC, Albert MS, Keene CD, Saykin AJ, Risacher SL, Larson EB, Sperling RA, Mayeux R, Goate AM, Renton AE, Marcora E, Fulton-Howard B, Patel T, Bennett DA, Schneider JA, Barnes LL, Cruchaga C, Hassenstab J, Belloy ME, Andrews SJ, Resnick SM, Bilgel M, An Y, Beason-Held LL, Walker KA, Duggan MR, Klinedinst BS, Crane PK, Hohman TJ Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease 2025 Aug;148(8):2714-2729. doi: 10.1093/brain/awaf106. Epub 2025-03-20. PubMed

Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, da Fonseca EL, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Ikeuchi T, Iqbal T, Pathak O, Valladares O, Reyes-Dumeyer D, Kuzma AB, Abner E, Adams LD, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Auerbach S, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Friedland RP, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Go RCP, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kikuchi M, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, Obisesan T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Petrovitch H, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sabbagh M, Sadovnick AD, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, George-Hyslop PS, Starks TD, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsolaki M, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Miyashita A, Byrd GS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC, Alzheimer’s Disease Genetics Consortium (ADGC) Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease 2025 Jul 17;26(1):210. doi: 10.1186/s13059-025-03564-z. Epub 2025-07-17. PubMed

Hayes-Larson E, Andrews RM, Kezios KL, Bercu A, Rouanet A, Helmer C, Crane PK, Gibbons LE, Klinedinst BS, McEvoy LK, Nichols E, Weuve J, Rajan KB, Hwang PH, Mez J, Farina M, Shaw C, Sims KD, Therneau T, Petersen RC, Bouteloup V, Gross AL, Albert M, Morris JC, Masters CL, Resnick SM, Maruff P, Manly JJ, Turney IC, Vonk JMJ, Avila-Rieger J, Weigand A, Chen R, Wang J, Proust-Lima C, Mayeda ER Approaches to timescale choice in cognitive aging research and potential implications for estimated exposure effects: coordinated analyses in ten cohorts of older adults 2025 Jul;36(4):560-571. doi: 10.1097/EDE.0000000000001859. Epub 2025-03-31. PubMed

Gray SL, Su YR, Eshetie TC, LaCroix AZ, Marcum ZA, Yu O Cumulative Anticholinergic Exposure and Change in Gait Speed and Grip Strength in Older Adults 2025 Jul;8(7):e2519819. doi: 10.1001/jamanetworkopen.2025.19819. Epub 2025-07-01. PubMed

Mossavar-Rahmani Y, Hyun N, Hakun JG, Katz MJ, Pavlovic JM, Zetterberg H, Wang Z, Yang JB, Wylie-Rosett J, Hebert JR, Sliwinski MJ, Shaw PA The effects of the Multicultural Healthy Diet on cognitive decline & Alzheimer's disease risk: A randomized controlled trial in middle-aged adults 2025 Jul;122(1):48-59. doi: 10.1016/j.ajcnut.2025.05.011. Epub 2025-05-20. PubMed

Posis AIB, Elman JA, Alcaraz JE, Parada H, Shadyab AH, Fennema-Notestine C, Hagler DJ, Lyons MJ, Panizzon MS, Reynolds CA, Franz CE, Kremen WS, McEvoy LK Associations of history of traumatic brain injury with markers of brain health among older men in the Vietnam Era Twin Study of Aging 2025 Jun 21;47:103831 doi:10.1016/j.nicl.2025.103831. doi: 10.1016/j.nicl.2025.103831. Epub 2025-06-21. PubMed