Recent publications on Aging & Geriatrics

Wang L, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin C, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD; for the National Institute on Aging–Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study; Alzheimer’s Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada MM, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin L, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, Kramer P, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam MM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu C, Yu L. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb;72(2):209-16. doi: 10.1001/jamaneurol.2014.2157. Epub 2014 Dec 22. PubMed

Singer A, Exuzides A, Spangler L, O'Malley C, Colby C, Johnston K, Agodoa I, Baker J, Kagan R. Burden of illness for osteoporotic fractures compared with other serious diseases among postmenopausal women in the United States. Mayo Clin Proc. 2015 Jan;90(1):53-62. doi: 10.1016/j.mayocp.2014.09.011. Epub 2014 Dec 4. PubMed

Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SL, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, Eiriksdottir G, Assareh AA, Kochan NA, Widen E, Palotie A, Hsieh YC, Eriksson JG, Vogler C, van Swieten JC, Shulman JM, Beiser A, Rotter J, Schmidt CO, Hoffmann W, Nöthen MM, Ferrucci L, Attia J, Uitterlinden AG, Amouyel P, Dartigues JF, Amieva H, Räikkönen K, Garcia M, Wolf PA, Hofman A, Longstreth WT Jr, Psaty BM, Boerwinkle E, DeJager PL, Sachdev PS, Schmidt R, Breteler MM, Teumer A, Lopez OL, Cichon S, Chasman DI, Grodstein F, Müller-Myhsok B, Tzourio C, Papassotiropoulos A, Bennett DA, Ikram AM, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH Jr; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Biol Psychiatry. 2015 Apr 15;77(8):749-63. doi: 10.1016/j.biopsych.2014.08.027. Epub 2014 Nov 25. PubMed

Caan B, LaCroix AZ, Joffe H, Guthrie KA, Larson JC, Carpenter JS, Cohen LS, Freeman EW, Manson JE, Newton K, Reed S, Rexrode K, Shifren J, Sternfeld B, Ensrud K. Effects of estrogen and venlafaxine on menopause-related quality of life in healthy postmenopausal women with hot flashes: a placebo-controlled randomized trial.  Menopause. 2015 Jun;22(6):607-15. doi: 10.1097/GME.0000000000000364. Epub 2014 Nov 17. PubMed

Shrira A, Zaslavsky O, LaCroix AZ, Seguin R, Post S, Tindle H, Hingle M, Woods N, Cochrane B, Garcia L, Schnall E, Rillamas-Sun E, Palgi Y. Global quality of life modifies terminal change in physical functioning among older adult women. Age Ageing. 2015 May;44(3):520-4. doi: 10.1093/ageing/afu176. Epub 2014 Nov 7. PubMed

Shadyab AH, LaCroix AZ. Genetic factors associated with longevity: a review of recent findings.  Ageing Res Rev. 2015 Jan;19:1-7. doi: 10.1016/j.arr.2014.10.005. Epub 2014 Nov 5. PubMed

Gourlay ML, Overman RA, Fine JP, Ensrud KE, Crandall CJ, Gass ML, Robbins J, Johnson KC, LeBlanc ES, Womack CR, Schousboe JT, LaCroix AZ. Baseline age and time to major fracture in younger postmenopausal women.  Menopause. 2015 Jun;22(6):589-97. doi: 10.1097/GME.0000000000000356. Epub 2014 Oct 27. PubMed

Ensrud KE, Guthrie KA, Hohensee C, Caan B, Carpenter JS, Freeman EW, LaCroix AZ, Landis CA, Manson J, Newton KM, Otte J, Reed SD, Shifren JL, Sternfeld B, Woods NF, Joffe H. Effects of estradiol and venlafaxine on insomnia symptoms and sleep quality in women with hot flashes. Sleep. 2015 Jan 1;38(1):97-108. doi: 10.5665/sleep.4332. Epub 2014 Oct 17. PubMed

Littman AJ, Thompson ML, Boyko EJ, Sangeorzan BJ, Haselkorn JK, Arterburn DE. Physical activity barriers and enablers in older veterans with a lower extremity amputation. J Rehabil Res Dev. 2014;51(6):895-906. doi: 10.1682/JRRD.2013.06.0152. PubMed

Rundell SD, Sherman KJ, Heagerty PJ, Mock C, Jarvik JG. Patient-reported outcomes associated with use of physical therapy services for older adults with a new visit for back pain.  Phys Ther. 2015 Feb;95(2):190-201. doi: 10.2522/ptj.20140132. Epub 2014 Oct 2. PubMed

Simon GE. Antidepressant prescribing in elderly populations: in reply.  Psychiatr Serv. 2014;65(10):1285-6. doi: 10.1176/appi.ps.651009.  PubMed

Thakral M, Shi L, Shmerling RH, Bean JF, Leveille SG. A stiff price to pay: does joint stiffness predict disability in an older population? J Am Geriatr Soc. 2014 Oct;62(10):1891-9. doi: 10.1111/jgs.13070. PubMed

Anderson LA, Slonim A, Yen IH, Jones DL, Allen P, Hunter RH, Goins RT, Leith KH, Rosenberg D, Satariano WA, McPhillips-Tangum C. Developing a framework and priorities to promote mobility among older adults. Health Educ Behav. 2014 Oct;41(1 Suppl):10S-8S. doi: 10.1177/1090198114537492. PubMed

Odden MC, Shlipak MG, Whitson HE, Katz R, Kearney PM, Defilippi C, Shastri S, Sarnak MJ, Siscovick DS, Cushman M, Psaty BM, Newman AB. Risk factors for cardiovascular disease across the spectrum of older age: the Cardiovascular Health Study. Atherosclerosis. 2014 Nov;237(1):336-42. doi: 10.1016/j.atherosclerosis.2014.09.012. Epub 2014 Sep 30. PubMed

Floyd JS, Sitlani CM, Wiggins KL, Wallace E, Suchy-Dicey A, Abbasi SA, Carnethon MR, Siscovick DS, Sotoodehnia N, Heckbert SR, McKnight B, Rice KM, Psaty BM. Variation in resting heart rate over 4 years and the risks of myocardial infarction and death among older adults. Heart. 2015 Jan;101(2):132-8. doi: 10.1136/heartjnl-2014-306046. Epub 2014 Sep 11. PubMed

Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA; and the Alzheimer Disease Genetics Consortium. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov;71(11):1394-404. doi: 10.1001/jamaneurol.2014.1491. Epub 2014 Sep 8. PubMed

Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of longevity in CHARGE Consortium confirms ApoE and FoxO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8. doi: 10.1093/gerona/glu166. Epub 2014 Sep 8. PubMed

Bell J, Fitzpatrick A, Copeland C, Chi G, Steinman L, Whitney RL, Atkins D, Bryant L, Grodstein F, Larson E, Logsdon R, Snowden M. Existing data resources to support studies of dementia or significant cognitive impairment and comorbid chronic conditions. Alzheimers Dement. 2015 Jun;11(6):622-38. doi: 10.1016/j.jalz.2014.07.002. Epub 2014 Sep 4. PubMed

Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P, Dickson DW, Farrer LA, Frosch MP, Ghetti B, Haines JL, Hyman BT, Kukull WA, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Reiman EM, Alzheimer's Disease Genetics Consortium (ADGC), Schellenberg GD, Montine TJ. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet. 2014 4;10(9):e1004606. doi: 10.1371/journal.pgen.1004606. eCollection 2014 Sep. PubMed

Zaslavsky O, Rillamas-Sun E, Woods NF, Cochrane BB, Stefanick ML, Tindle H, Tinker LF, LaCroix AZ. Association of the selected dimensions of eudaimonic well-being with healthy survival to 85 years of age in older women.  Int Psychogeriatr. 2014 Dec;26(12):2081-91. doi: 10.1017/S1041610214001768. Epub 2014 Aug 27. PubMed