Recent publications on Aging & Geriatrics

Rossom R, Knowlton G, Yeh HH, Penfold R, Owen-Smith A, Hooker S, Simon G, Miller-Matero L, Akinyemi E, Ahmedani B. Psychotherapy engagement before and after a rapid transition to telehealth during COVID-19 for older adults with dementia. J Appl Gerontol. 2024 Aug 5:7334648241271922. doi: 10.1177/07334648241271922. [Epub ahead of print]. PubMed

Nguyen S, McEvoy LK, Espeland MA, Whitsel EA, Lu A, Horvath S, Manson JE, Rapp SR, Shadyab AH. Associations of epigenetic age estimators with cognitive function trajectories in the Women's Health Initiative Memory study. Neurology. 2024 Jul 9;103(1):e209534. doi: 10.1212/WNL.0000000000209534. Epub 2024 Jun 10. PubMed

Phelan EA, Williamson BD, Balderson BH, Cook AJ, Piccorelli AV, Fujii MM, Nakata KG, Graham VF, Theis MK, Turner JP, Tannenbaum C, Gray SL. Reducing central nervous system-active medications to prevent falls and injuries among older adults: a cluster randomized clinical trial. JAMA Netw Open. 2024 Jul 1;7(7):e2424234. doi: 10.1001/jamanetworkopen.2024.24234. PubMed

Rosenberg DE, Wu Y, Idu A, Greenwood-Hickman MA, McCurry SM, LaCroix AZ, Shaw PA. Historic cognitive function trajectories as predictors of sedentary behavior and physical activity in older adults. J Gerontol A Biol Sci Med Sci. 2024;79(7):glae125. doi: 10.1093/gerona/glae125.  PubMed

Karter AJ, Parker MM, Huang ES, Seligman HK, Moffet HH, Ralston JD, Liu JY, Gilliam LK, Laiteerapong N, Grant RW, Lipska KJ. Food insecurity and hypoglycemia among older patients with type 2 diabetes treated with insulin or sulfonylureas: the Diabetes & Aging Study. J Gen Intern Med. 2024 May 20. doi: 10.1007/s11606-024-08801-y. [Epub ahead of print]. PubMed

Rosenberg DE, Zhu W, Greenwood-Hickman MA, Cook AJ, Florez Acevedo S, McClure JB, Arterburn DE, Cooper J, Owen N, Dunstan D, Perry SR, Yarborough L, Mettert KD, Green BB. Sitting Time Reduction and Blood Pressure in Older Adults: A Randomized Clinical Trial.  JAMA Netw Open. 2024;7(3):e243234. doi: 10.1001/jamanetworkopen.2024.3234.  PubMed

Mossa-Basha M, Andre JB, Yuh E, Hunt D, LaPiana N, Howlett B, Krakauer C, Crane P, Nelson J, DeZelar M, Meyers K, Larson E, Ralston J, Mac Donald CL. Comparison of brain imaging and physical health between research and clinical neuroimaging cohorts of ageing.  Br J Radiol. 2024;97(1155):614-621. doi: 10.1093/bjr/tqae004.  PubMed

Harrington LB, Ehlert AN, Thacker EL, Jenny NS, Lopez O, Cushman M, Olson NC, Fitzpatrick A, Mukamal KJ, Jensen MK. Levels of procoagulant factors and peak thrombin generation in relation to dementia risk in older adults: The Cardiovascular Health Study.  Thromb Res. 2024;235:148-154. doi: 10.1016/j.thromres.2024.01.024. Epub 2024 Feb 4.  PubMed

Reas ET, Triebswetter C, Banks SJ, McEvoy LK. Effects of APOE2 and APOE4 on brain microstructure in older adults: modification by age, sex, and cognitive status.  Alzheimers Res Ther. 2024;16(1):7. doi: 10.1186/s13195-023-01380-w.  PubMed

Cholerton B, Latimer CS, Crane PK, Corrada MM, Gibbons LE, Larson EB, Kawas CH, Keene CD, Montine TJ. Neuropathologic burden and dementia in nonagenarians and centenarians: Comparison of 2 community-based cohorts. Neurology. 2024;102(3):e208060. doi: 10.1212/WNL.0000000000208060. Epub 2024 Jan 4.  PubMed

Yaffe K, Vittinghoff E, Dublin S, Peltz CB, Fleckenstein LE, Rosenberg DE, Barnes DE, Balderson BH, Larson EB. Effect of personalized risk-reduction strategies on cognition and dementia risk profile among older adults: the SMARRT randomized clinical trial. JAMA Intern Med. 2024 Jan 1;184(1):54-62. doi: 10.1001/jamainternmed.2023.6279. PubMed

Posis AIB, Shadyab AH, Parada H, Alcaraz JE, Kremen WS, McEvoy LK. Multimorbidity, social engagement, and age-related cognitive decline in older adults from the Rancho Bernardo study of healthy aging. J Alzheimers Dis. 2024;97(4):1689-1702. doi: 10.3233/JAD-230809.  PubMed

Dublin S, Greenwood-Hickman MA, Karliner L, Hsu C, Coley RY, Colemon L, Carrasco A, King D, Grace A, Lee SJ, Walsh JME, Barrett T, Broussard J, Singh U, Idu A, Yaffe K, Boustani M, Barnes DE. The electronic health record Risk of Alzheimer's and Dementia Assessment Rule (eRADAR) Brain Health Trial: Protocol for an embedded, pragmatic clinical trial of a low-cost dementia detection algorithm.  Contemp Clin Trials. 2023;135:107356. doi: 10.1016/j.cct.2023.107356. Epub 2023 Oct 17.  PubMed

Tibiriçá L, Jester DJ, Kohn JN, Williams AP, McEvoy LK, Palmer BW. Perceived discrimination and nativity status: Risk of cognitive impairment among Latin American older adults. Int Psychogeriatr. 2024 Sep;36(9):818-830. doi: 10.1017/S1041610223004374. PubMed

McEvoy LK, Bergstrom J, Hagler DJ, Wing D, Reas ET. Elevated pure tone thresholds predict altered microstructure in cortical areas related to auditory processing and attentional allocation. J Alzheimers Dis. 2023 Nov 6. doi: 10.3233/JAD-230767. Online ahead of print. PubMed

Simone T, Peltz C, Rosenberg DE, Barnes DE, Fleckenstein LE, Dublin S, Yaffe K. The Impact of Pandemic-Related Restrictions on Dementia Risk Factors in Older Adults.  J Appl Gerontol. 2023 Nov 6:7334648231210671. doi: 10.1177/07334648231210671 [Epub ahead of print] PubMed

Hyde ET, Tuz-Zahra F, Moore CC, Natarajan L, Nguyen S, Greenwood-Hickman MA, Walker RL, Rosenberg DE, Bellettiere J. Agreement of step-based metrics from ActiGraph and activPAL accelerometers worn concurrently among older adults. J Meas Phys Behav. 2022 Dec;5(4):242-251. doi: 10.1123/jmpb.2022-0001. Epub 2022 Oct 11. PubMed

Lee AK, Lee SJ, Dublin S. Addressing the unique challenges in studies of long-term medication use and dementia risk. J Am Geriatr Soc. 2023 Oct;71(10):3028-3030. doi: 10.1111/jgs.18583. Epub 2023 Sep 7. PubMed

Wang X, Sundermann EE, Buckley RF, Reas ET, McEvoy LK, Banks SJ; A4 Study Team. Sex differences in the associations of obesity with Tau, amyloid PET, and cognitive outcomes in preclinical Alzheimer's disease: Cross-sectional A4 study. J Alzheimers Dis. 2023 Aug 7. doi: 10.3233/JAD-230466. Online ahead of print. PubMed

Balderson BH, Gray SL, Fujii MM, Nakata KG, Williamson BD, Cook AJ, Wellman R, Theis MK, Lewis CC, Key D, Phelan EA. A health-system-embedded deprescribing intervention targeting patients and providers to prevent falls in older adults (STOP-FALLS trial): Study protocol for a pragmatic cluster-randomized controlled trial. Trials. 2023 May 11;24(1):322. doi: 10.1186/s13063-023-07336-7. PubMed