Blood pressure measurements routinely taken at home are more likely to provide the basis for accurate diagnoses of hypertension than those taken in a clinic setting, according to a new study led by Kaiser Permanente investigators.
The findings — published in the Journal of General Internal Medicine — come from a randomized controlled trial of 510 adults who visited 1 of 12 Kaiser Permanente primary care centers in Western Washington between 2017 and 2019.
“Blood pressure varies a lot over the day — about 30 points systolic — and 1 or 2 measurements in clinic may not reflect your average blood pressure,” said Beverly B. Green, MD. MPH, the study’s lead author, who is a senior investigator at Kaiser Permanente Washington Health Research Institute and a physician at Washington Permanente Medical Group. “Home blood pressure monitoring allows you to collect many more readings and average these.”
To conduct the study, researchers used electronic health records to identify potential participants who were at high risk of having hypertension based on a recent clinic visit. They then randomly divided the participants into groups to obtain follow-up blood pressure measurements using 1 of 3 methods: in a clinic, at home, or at kiosks in medical clinics or pharmacies.
Every participant also received 24-hour ambulatory blood pressure monitoring, or ABPM — the gold standard test for making a new diagnosis of hypertension. ABPM uses a full upper-arm cuff connected to a waist-carried device that is worn continuously for 24 hours and inflates every 20 to 30 minutes during the day and every 30 to 60 minutes at night. ABPM provides the most precise diagnostic information but is not available for widespread use. The researchers were able to determine the accuracy of the 3 other methods by comparing their results with the ABPM results.
The study found:
“Home blood pressure monitoring was a better option, because it was more accurate than clinic blood pressure readings,” Dr. Green said. “Furthermore, a companion study found that patients preferred taking their blood pressure at home.” The companion study findings were presented at an American Heart Association Hypertension meeting.
The number of people in the U.S. with undiagnosed hypertension is likely to be in the millions. One recent analysis published in JAMA estimated that 23% of U.S. adults with high blood pressure were unaware that they had the condition and were not receiving treatment.
Proper diagnosis of hypertension can save a patient’s life. When hypertension is identified, physicians will typically prescribe medication to lower blood pressure. Without treatment, hypertension can cause heart attacks, strokes, and kidney damage, among other problems.
Current guidelines for diagnosing hypertension recommend that patients who have high blood pressure readings in clinic have another test to confirm the results. While the guidelines recommend ABPM or home blood pressure monitoring before making a hypertension diagnosis, research shows that many providers continue to use in-clinic measurement when conducting the second reading.
While previous studies have found similar benefits to home blood pressure reading, this trial may offer the most powerful evidence to date because of its large number of participants, its involvement of primary care clinics, and its use of real-world practitioners to take blood pressure measures instead of research personnel. Also, this study is the first to compare kiosk and ABPM results.
Research led by KPWHRI’s Beverly Green, MD, MPH, finds that patients prefer at-home monitoring of blood pressure.
KPWHRI investigator’s recent AHA presentations highlight problems in blood pressure readings.
Dr. Beverly Green, PCORI-funded BP-CHECK leader, reflects on her professional interest in hypertension getting up close and personal.