Greg Simon, MD, MPH, is a psychiatrist and senior investigator well-known for his extensive research on practical approaches to improving mental health care. He seeks to develop and evaluate effective real-world strategies that support better mental health and wellness. Current areas of emphasis include identifying and assessing suicide risk, improving care for treatment-resistant depression, and early intervention for mental health conditions in children and youth.
Dr. Simon leads the Mental Health Research Network (MHRN), a consortium of research centers affiliated with 13 large health systems across the United States, including Kaiser Permanente Washington. This network, funded through a cooperative agreement with the National Institute of Mental Health, aims to improve the efficiency, relevance, and impact of mental health clinical and health services research. Now in its second five-year funding cycle, the MHRN is exploring a broad range of issues—including suicide prevention, improving heart health in people with serious mental illness, using electronic medical records to improve follow-up care for depression, and understanding the causes of racial and ethnic disparities in mental health care.
Dr. Simon and his MHRN colleagues are conducting several large studies across MHRN health systems, including:
Dr. Simon is an editor for the Cochrane Collaboration’s depression and anxiety review group, sits on the editorial board for General Hospital Psychiatry, and serves on the advisory board for the National Institutes of Health’s All of Us Program (formerly Precision Medicine Initiative). Earlier, he served on the editorial boards of Psychiatric Services and Psychological Medicine and chaired the scientific advisory board for the Depression and Bipolar Support Alliance. Dr. Simon has practiced adult psychiatry in Kaiser Permanente Washington's Mental Health and Wellness Service since 1990 and is a research professor in psychiatry and behavioral sciences at the University of Washington.
Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS. Factors that impact treatment decisions: results from an online survey of individuals with bipolar and unipolar depression. Prim Care Companion CNS Disord. 2018 Nov 1;20(6). pii: 18m02340. doi: 10.4088/PCC.18m02340. PubMed
Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS. Frequency of use and perceived helpfulness of wellness strategies for bipolar and unipolar depression. Ann Clin Psychiatry. 2018;30(4):296-304. PubMed
Simon GE. Why integrated care already owns the future. Fam Pract. 2018 Sep 26. pii: 5107523. doi: 10.1093/fampra/cmy095. [Epub ahead of print]. PubMed
Rosenblat JD, Simon GE, Sachs GS, Deetz I, Doederlein A, DePeralta D, Dean MM, McIntyre RS. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. J Affect Disord. 2019;243:116-120. doi: 10.1016/j.jad.2018.09.027. Epub 2018 Sep 12. PubMed
Simon GE, Johnson E, Lawrence JM, Rossom RC, Ahmedani B, Lynch FL, Beck A, Waitzfelder B, Ziebell R, Penfold RB, Shortreed SM. Predicting suicide attempts and suicide deaths following outpatient visits using electronic health records. Am J Psychiatry. 2018 May 24:appiajp201817101167. doi: 10.1176/appi.ajp.2018.17101167. [Epub ahead of print]. PubMed
Ludman EJ, Simon GE, Whiteside U, Richards JE, Pabiniak C. Reevaluating sensitivity of self-reported suicidal ideation. J Clin Psychiatry. 2018 May/Jun;79(3). pii: 17l12017. doi: 10.4088/JCP.17l12017. PubMed
Lu CY, Simon G, Soumerai SB. Counter-point: staying honest when policy changes backfire. Med Care. 2018 May;56(5):384-390. doi: 10.1097/MLR.0000000000000897. PubMed
Lu CY, Simon G, Soumerai SB, Kulldorff M. Counter-point: early warning systems are imperfect, but essential. Med Care. 2018 May;56(5):382-383. doi: 10.1097/MLR.0000000000000896. PubMed
Lu CY, Penfold RB, Toh S, Sturtevant JL, Madden JM, Simon G, Ahmedani BK, Clarke G, Coleman KJ, Copeland LA, Daida YG, Davis RL, Hunkeler EM, Owen-Smith A, Raebel MA, Rossom R, Soumerai SB, Kulldorff M. Near real-time surveillance for consequences of health policies using sequential analysis. Med Care. 2018 May;56(5):365-372. doi: 10.1097/MLR.0000000000000893. PubMed
Coleman KJ, Johnson E, Ahmedani BK, Beck A, Rossom RC, Shortreed SM, Simon GE. Predicting suicide attempts for racial and ethnic groups of patients during routine clinical care. Suicide Life Threat Behav. 2019 Jun;49(3):724-734. doi: 10.1111/sltb.12454. Epub 2018 Mar 24. PubMed
KPWHRI researchers are contributing to better mental health care for people nationwide.
Models that are easier to explain, use could have better uptake in health care settings.
Findings provide roadmap for addressing barriers and improving suicide prevention.
Kaiser Permanente physician-scientist will receive American Foundation for Suicide Prevention's Lifesavers Research Award.
STAT News, May 2, 2023