Laura E. Ichikawa, MS

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"KPWHRI provides a great opportunity to collaborate with multidisciplinary teams and provide biostatistical support to improve patient health."

Laura E. Ichikawa, MS

Principal Collaborative Biostatistician, Kaiser Permanente Washington Health Research Institute

Biography

With more than 25 years at Kaiser Permanente Washington Health Research Institute (KPWHRI), Laura Ichikawa, MS, is known for her analytical skills, attention to detail regarding study design and data management, and expertise in data visualization. Her experience includes observational studies, randomized controlled trials, case-control studies, and multisite analyses.

Laura is primarily focused on cancer research and women’s health. She’s involved in 2 large, multisite National Cancer Institute-funded projects: the Statistical Coordinating Center for the Breast Cancer Surveillance Consortium (BCSC) and a colorectal research site for Population-based Research to Optimize the Screening Process (PROSPR). Much of her work with the BCSC has been evaluating mammography performance for both screening and surveillance while also examining use of screening MRI (magnetic resonance imaging) and ultrasound. Laura also participated in collaborative research through the Cancer Research Network, including a widely publicized 2004 study that linked not having screening mammograms to late-stage breast cancer. She is excited to continue her work in cancer research, including in screening, treatment, surveillance, and survival.

Laura’s earlier research with retired KPWHRI Senior Investigator Delia Scholes, PhD, included studies examining bone loss associated with the injectable hormonal contraceptive Depo-Provera in 2002 and 2005 and oral contraceptives in 2011.

Laura is a member of the American Statistical Association and its Puget Sound chapter.

Research interests and experience

  • Biostatistics

    Longitudinal data analysis

  • Cancer

    Biostatistics; breast cancer

  • Women's Health

    Biostatistics; hormonal contraception and bone density

Recent publications

Arterburn D, Ichikawa L, Ludman E, Operskalski B, Linde J, Anderson E, Rohde P, Jeffery R, Simon G. Validity of clinical body weight measures as substitutes for missing data in a randomized trial. Obesity Research and Clinical Practice. 2008;10(4):277-81.

Ott SM, Ichikawa LE, LaCroix AZ, Scholes D. Navel jewelry artifacts and intravertebral variation in spine bone densitometry in adolescents and young women.  J Clin Densitom. 2009 Jan-Mar;12(1):84-8. Epub 2008 Nov 5. PubMed

Rohde P, Ichikawa L, Simon GE, Ludman EJ, Linde JA, Jeffery RW, Operskalski BH. Associations of child sexual and physical abuse with obesity and depression in middle-aged women.  Child Abuse Negl. 2008;32(9):878-87. Epub 2008 Oct 22. PubMed

Jeffery RW, Linde JA, Simon GE, Ludman EJ, Rohde P, Ichikawa LE, Finch EA. Reported food choices in older women in relation to BMI and depressive symptoms.  Appetite. 2009 Feb;52(1):238-40. Epub 2008 Aug 28. PubMed

Ott SM, Lacroix AZ, Scholes D, Ichikawa LE, Wu K. Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons.  Osteoporos Int. 2008;19(9):1315-22. Epub 2008 Apr 19. PubMed

Tice JA, Cummings SR, Smith-Bindman R, Ichikawa L, Barlow WE, Kerlikowske K. Using clinical factors and mammographic breast density to estimate breast cancer risk: development and validation of a new predictive model.  Ann Intern Med. 2008;148(5):337-47. PubMed

Jeffery RW, Finch EA, Linde JA, Simon GE, Ludman EJ, Operskalski BH, Rohde P, Ichikawa LE. Does clinical depression affect the accuracy of self-reported height and weight in obese women?  Obesity (Silver Spring). 2008;16(2):473-5. PubMed

Simon GE, Ludman EJ, Linde JA, Operskalski BH, Ichikawa L, Rohde P, Finch EA, Jeffery RW. Association between obesity and depression in middle-aged women. Gen Hosp Psychiatry. 2008;30(1):32-9. PubMed

Wetmore CM, Ichikawa L, Lacroix AZ, Ott SM, Scholes D. Association between caffeine intake and bone mass among young women: potential effect modification by depot medroxyprogesterone acetate use. Osteoporos Int. 2008;19(4):519-27. Epub 2007 Oct 9. PubMed

Buist DS, Ichikawa L, Prout MN, Yood MU, Field TS, Owusu C, Geiger AM, Quinn VP, Wei F, Silliman RA. Receipt of appropriate primary breast cancer therapy and adjuvant therapy are not associated with obesity in older women with access to health care. J Clin Oncol. 2007;25(23):3428-36. PubMed

 

Research

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IUD perforation: Rare but important to know about

New study results in more precise language in the federally mandated warning about this possibility.

cancer research

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Using breast MRI after cancer may lead to unneeded biopsies

A Kaiser Permanente-led BCSC study is among the largest ever to evaluate adding MRI surveillance for breast cancer survivors.

cancer screening

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No need to follow up simple ovarian cysts

New KPWHRI study shows that women with simple cysts are not at increased risk of ovarian cancer.

aging & geriatrics

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Study finds various treatments can reduce vaginal discomfort from sex

Dr. Katherine Newton co-wrote JAMA Internal Medicine paper comparing vaginal estrogen, moisturizer, and placebo gel.