Weiwei Zhu, MS, joined Kaiser Permanente Washington Health Research Institute's Biostatistics Unit in 2009. She works closely with Affiliate Investigator Diana Miglioretti, PhD, to design studies, manage data, and conduct statistical analyses for the Breast Cancer Surveillance Consortium (BCSC) — the National Cancer Institute’s 7-site network of mammography researchers. She has been a key member of the BCSC Statistical Coordinating Center for over 10 years. Her work studying breast screening benefits and risks played an essential role in an American Cancer Society screening guideline change in 2015.
Weiwei’s current other studies include testing the effects of sitting reduction on cardiometabolic health outcomes through a large randomized trial in older adults, studying a sedentary behavior reduction and physical activity promotion intervention for the older Latino/Hispanic community, and examining the association of the 24-hour activity cycle with cognition and physical function in older adults with Senior Investigator Dori Rosenberg, PhD, MPH. Weiwei has also collaborated on research to quantify the serious risks of misuse, abuse, and addiction associated with long-term opioid use. This multi-site study used electronic health record data and survey interviews to provide estimates of long-term opioid use risks in 2 cohorts.
After beginning her medical research career as an intern at the University of Texas MD Anderson Cancer Center in 2007, Weiwei served as a biostatistician at the Moffitt Cancer Center and Research Institute in Florida.
Correlated data analysis; longitudinal data; survival analysis
Opioid misuse, abuse, and addiction
Biostatistics; breast cancer screening and surveillance
Henderson LM, Hubbard RA, Zhu W, Weiss J, Wernli KJ, Goodrich ME, Kerlikowske K, DeMartini W, Ozanne EM, Onega T. Preoperative breast magnetic resonance imaging use by breast density and family history of breast cancer. J Womens Health (Larchmt). 2018 Jan 15. doi: 10.1089/jwh.2017.6428. [Epub ahead of print]. PubMed
Onega T, Weiss JE, Goodrich ME, Zhu W, DeMartini WB, Kerlikowske K, Ozanne E, Tosteson ANA, Henderson LM, Buist DSM, Wernli KJ, Herschorn SD, Hotaling E, O'Donoghue C, Hubbard R. Relationship between preoperative breast MRI and surgical treatment of non-metastatic breast cancer. J Surg Oncol. 2017 Dec;116(8):1008-1015. doi: 10.1002/jso.24796. Epub 2017 Nov 11. PubMed
Henderson LM, Hubbard RA, Sprague BL, Zhu W, Kerlikowske K. Increased risk of developing breast cancer after a false-positive screening mammogram. Cancer Epidemiol Biomarkers Prev. 2015;24(12):1882-9. doi: 10.1158/1055-9965.EPI-15-0623. PubMed
Miglioretti DL, Zhu W, Kerlikowske K, Sprague BL, Onega T, Buist DS, Henderson LM, Smith RA. Breast tumor prognostic characteristics and biennial vs annual mammography, age, and menopausal status. JAMA Oncol. 2015 Nov 1;1(8):1069-77. doi: 10.1001/jamaoncol.2015.3084. PubMed
Kerlikowske K, Zhu W, Tosteson AN, Sprague BL, Tice JA, Lehman C,Miglioretti DL. Identifying women with dense breasts at high risk of interval cancers. Ann Intern Med. 2015;162(10):I-10. doi:10.7326/P15-9018. PubMed
New research spotlights overdiagnosis, MRI before surgery, and a new way of predicting breast cancer risk
Findings in JAMA Network Open could help guide decision-making about breast cancer screening for women 75 and older.
A study among KP members with sleep problems and osteoarthritis shows promise for overcoming obstacles to treatment.