Robert Penfold, PhD

Robert Penfold

“I do research designed to improve real-world mental health care.” 

Robert Penfold, PhD

Senior Investigator, Kaiser Permanente Washington Health Research Institute

Biography

Robert Penfold, PhD, is a health services research and health policy expert whose work focuses on developing and testing strategies to optimize behavioral health care delivery and patient outcomes—particularly in children and adolescents. His research addresses practical issues, such as how to reduce unnecessary use of antipsychotic medications in youth. He also studies the effects of cost-control policies on how clinicians deliver care, how people use care, and how those changes can promote or worsen their health.

Dr. Penfold is a co-investigator in the Mental Health Research Network (MHRN), a resource for studies on mental health conditions ranging from autism to postnatal depression. He leads the MHRN’s child and adolescent scientific interest group. He is also investigating reasons why similar patients receive different mental health treatment, such as different medications, depending on where they live or receive care.

His other recent and ongoing projects include:

  • A Targeted Approach to a Safer Use of Antipsychotics in Youth (SUAY), a $10 million, five-year National Institutes of Health clinical trial that is developing and testing new ways to support clinicians and families in choosing safer treatments for behavioral disorders in youth age 5 to 17.
  • Assisted Identification and Navigation of Early Mental Health Symptoms in Youth. A National Institute of Mental Health (NIMH)-funded clinical trial designed to increase the early identification and treatment of youth with mental health symptoms and complaints.
  • Automated Outreach for Depression, a NIMH-funded study to decrease premature dropout from depression treatment.
  • STAR Caregivers—Virtual Training and Follow-up, a National Institute on Aging funded clinical trial to improve the behavioral and psychological symptoms of dementia and reduce caregiver burden without the use of antipsychotic medications.

Dr. Penfold has extensive experience gathering and analyzing information from large health databases, including those of Medicare, Medicaid, and the Health Care Systems Research Network’s Virtual Data Warehouse. These data and analyses allow rapid information sharing among Kaiser Permanente Washington and participating sites, which improves patient safety and timely access to effective, cutting-edge therapies.

He has also conducted several novel pragmatic clinical trials using the Epic electronic health record system.  

Before joining KPWHRI in 2010, Dr. Penfold held research and teaching positions at Nationwide Children's Hospital in Columbus, Ohio; the Winnipeg Regional Health Authority; the Manitoba Centre for Health Policy; and most recently, at Harvard Medical School in the Department of Population Medicine and Harvard Pilgrim Health Care Institute.

Research interests and experience

  • Mental Health

    Children and adolescents; anti-psychotics and anti-depressants; bipolar disorder, and depression

  • Health Services & Economics

    Comparative effectiveness; consumer-directed health plans; patient outcomes; costs of chronic illnesses; Medicare and Medicaid 

  • Biostatistics

    Space-time surveillance;  interrupted time series analysis

  • Alzheimer's Disease and Related Dementias

Recent publications

Penfold RB, Yoo HI, Richards JE, Crossnohere NL, Johnson E, Pabiniak CJ, Renz AD, Campoamor NB, Simon GE, Bridges JFP. Acceptability of linking individual credit, financial, and public records data to healthcare records for suicide risk machine learning models.  JAMIA Open. 2024 Oct 21;7(4):ooae113. doi: 10.1093/jamiaopen/ooae113. eCollection 2024.  PubMed

Penfold RB, Idu AE, Coley RY, Cushing-Haugen KL, King D, Glass A, Phillips RC, Renz AD, Pabiniak CJ, Graham VF, Thompson EE, Ralston JD, Simon GE, Gonzalez ES, Myers KM, Beck A, Quintana LM, Runkle AJ, Rogers M, Foster DM, Clarke GN, Massimino S, Crawford PM, Cavese JA, Cordaro AR, Chavez LI, Kelleher KJ, Schwartz N, Jiner KR, Liu SB, Condrac S, Hilt RJ. Safer and targeted use of antipsychotics in youth: an embedded, pragmatic randomized trial. J Child Psychol Psychiatry. 2024 Oct 29. doi: 10.1111/jcpp.14059. Epub ahead of print]. PubMed

Desai RJ, Marsolo K, Smith J, Carrell D, Penfold R, Pillai HS, Lii J, Ngan K, Winter R, Adgent M, Ramaprasan A, Driscoll MR, Scarnecchia D, Kiernan D, Draper C, Lyons JG, Khurshid A, Maro JC, Zimmerman R, Brown J, Bright P, Hernández-Muñoz JJ, Matheny ME, Schneeweiss S. The FDA sentinel Real World Evidence Data Enterprise (RWE-DE). Pharmacoepidemiol Drug Saf. 2024;33(10):e70028. doi: 10.1002/pds.70028.  PubMed

Grosvenor LP, Croen LA, Lynch FL, Marafino BJ, Maye M, Penfold RB, Simon GE, Ames JL. Autism diagnosis among US children and adults, 2011-2022. JAMA Netw Open. 2024;7(10):e2442218. doi: 10.1001/jamanetworkopen.2024.42218.  PubMed

Boggs JM, Yarborough BJH, Clarke G, Aguirre-Miyamoto EM, Barton LJ, Beck A, Bruschke C, Buttlaire S, Coleman KJ, Flores JP, Penfold R, Powers JD, Richards JA, Richardson L, Runkle A, Ryan JM, Simon GE, Sterling S, Stewart C, Stumbo S, Quintana LM, Yeh HH, Ahmedani BK. Development and validation of electronic health record measures of safety planning practices as part of zero suicide implementation.  Arch Suicide Res. 2024 Aug 28:1-14. doi: 10.1080/13811118.2024.2394676. [Epub ahead of print]. PubMed

 

Research

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Latino families inform training for caregivers of people with dementia

Maggie Ramirez, PhD, and Robert Penfold, PhD, culturally adapt an online program.

Research

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Improving and advancing mental health care

KPWHRI researchers are contributing to better mental health care for people nationwide.

New findings

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Simpler models to identify suicide risk perform similarly to more complex ones

Models that are easier to explain, use could have better uptake in health care settings.

HCSRN conference

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Researchers present, connect at annual conference

The HCSRN conference is a venue for collaborative work to improve health and health care.