James D. Ralston, MD, MPH

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“My work focuses on helping patients who live with common chronic health conditions.”

James D. Ralston, MD, MPH

Senior Investigator, Kaiser Permanente Washington Health Research Institute
Physician, Washington Permanente Medical Group, Internal Medicine

Biography

James Ralston MD, MPH, is an internal medicine physician and senior investigator in health services and health informatics. His research mission is improving the health and care of patients living with common ongoing illnesses. His current areas of emphasis include understanding and honoring the priorities of patients living with multiple chronic conditions.

Dr. Ralston’s research focuses on developing and evaluating communication technologies that foster continuous care and a closer connection between patients and primary care teams. His commitment to finding effective ways to redesign care spans all stages of research, from project development to complete translation of results into clinical practice.

Examples of Dr. Ralston’s research projects include:

  • The Valuing Important Things in Active Lives (VITAL) study to improve care for people with multiple chronic conditions including diabetes, heart disease, and arthritis. VITAL uses participatory design methods with patients and providers to design and evaluate interactive care plans.
  • The Seeing Priorities study to build and test a single, trusted tool for individuals with multiple chronic conditions that illuminates connections between personal values and chronic illness management. The tool helps visualize, track, and share what matters most for self-management and care. 
  • Understanding and addressing differences in patient use of online health care services that could lead to care disparities.
  • Testing online care management of blood sugar control using an electronic health record shared with patients with type 2 diabetes. Control improved in patients receiving online care management in addition to usual care.
  • Validating and evaluating a clinical tool to identify patients with type 2 diabetes at risk of severe low blood sugar. This national collaboration uses Kaiser Permanente and Veterans Administration electronic health record data and machine learning methods.
  • Testing innovative engagement methods such as photos taken by study participants to document their values to ensure that patient priorities guide self-management plans and clinical care.
  • Working with primary care teams and clinics in rural and underserved areas to improve the care of their patients with chronic conditions.

Dr. Ralston is also a University of Washington affiliate professor in health services and biomedical informatics, where he serves on the committees of PhD and master’s degree students.

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Research interests and experience

Recent publications

Blasi PR, Scrol A, Anderson ML, Gray MF, Tiffany B, Fullerton SM, Ralston JD, Leppig KA, Henrikson NB Feasibility, acceptability, and limited efficacy of health system-led familial risk notification: protocol for a mixed-methods evaluation 2022 Aug 9;8(1):174. doi: 10.1186/s40814-022-01142-9. Epub 2022-08-09. PubMed

Miller-Rosales C, McCloskey J, Uratsu CS, Ralston JD, Bayliss EA, Grant RW Associations Between Different Self-reported Social Risks and Neighborhood-level Resources in Medicaid Patients 2022 Aug;60(8):563-569. doi: 10.1097/MLR.0000000000001735. Epub 2022-05-30. PubMed

Bell SK, Bourgeois F, DesRoches CM, Dong J, Harcourt K, Liu SK, Lowe E, McGaffigan P, Ngo LH, Novack SA, Ralston JD, Salmi L, Schrandt S, Sheridan S, Sokol-Hessner L, Thomas G, Thomas EJ Filling a gap in safety metrics: development of a patient-centred framework to identify and categorise patient-reported breakdowns related to the diagnostic process in ambulatory care 2022 Jul;31(7):526-540. doi: 10.1136/bmjqs-2021-013672. Epub 2021-10-16. PubMed

Leppig KA, Kulchak Rahm A, Appelbaum P, Aufox S, Bland ST, Buchanan A, Christensen KD, Chung WK, Clayton EW, Crosslin D, Denny J, DeVange S, Gordon A, Green RC, Hakonarson H, Harr MH, Henrikson N, Hoell C, Holm IA, Kullo IJ, Jarvik GP, Lammers PE, Larson EB, Lindor NM, Marasa M, Myers MF, Perez E, Peterson JF, Pratap S, Prows CA, Ralston JD, Rasouly HM, Roden DM, Sharp RR, Singh R, Shaibi G, Smith ME, Sturm A, Thiese HA, Van Driest SL, Williams J, Williams MS, Wynn J, Blout Zawatsky CL, Wiesner GL The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network 2022 May;24(5):1130-1138. doi: 10.1016/j.gim.2022.01.015. Epub 2022-02-22. PubMed

McCloskey JK, Ellis JL, Uratsu CS, Drace ML, Ralston JD, Bayliss EA, Grant RW Accounting for Social Risk Does not Eliminate Race/Ethnic Disparities in COVID-19 Infection Among Insured Adults: a Cohort Study 2022 Apr;37(5):1183-1190. doi: 10.1007/s11606-021-07261-y. Epub 2022-02-02. PubMed

Patel HV, Henrikson NB, Ralston JD, Leppig K, Scrol A, Jarvik GP, DeVange S, Larson EB, Hartzler AL Implementation matters: How patient experiences differ when genetic counseling accompanies the return of genetic variants of uncertain significance 2022 Feb 21;2021:950-958. Epub 2022-02-21. PubMed

Schuttner L, Hockett Sherlock S, Simons C, Ralston JD, Rosland AM, Nelson K, Lee JR, Sayre G Factors affecting primary care physician decision-making for patients with complex multimorbidity: a qualitative interview study 2022 Feb 5;23(1):25. doi: 10.1186/s12875-022-01633-x. Epub 2022-02-05. PubMed

Ralston JD, Yu O, Penfold RB, Gundersen G, Ramaprasan A, Schartz EM Changes in Clinician Attitudes Toward Sharing Visit Notes: Surveys Pre-and Post-Implementation 2021 Nov;36(11):3330-3336. doi: 10.1007/s11606-021-06729-1. Epub 2021-04-22. PubMed

Tchesnokova V, Kulasekara H, Larson L, Bowers V, Rechkina E, Kisiela D, Sledneva Y, Choudhury D, Maslova I, Deng K, Kutumbaka K, Geng H, Fowler C, Greene D, Ralston J, Samadpour M, Sokurenko E Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-CoV-2 variants 2021 Oct 19;59(11):e0092121. doi: 10.1128/JCM.00921-21. Epub 2021-08-11. PubMed

Venner, Eric, Yi, Victoria, Murdock, David, Kalla, Sara E, Wu, Tsung-Jung, Sabo, Aniko, Li, Shoudong, Meng, Qingchang, Tian, Xia, Murugan, Mullai, Cohen, Michelle, Kovar, Christie, Wei, Wei-Qi, Chung, Wendy K, Weng, Chunhua, Wiesner, Georgia L, Jarvik, Gail P, Muzny, Donna, Gibbs, Richard A, Abrams, Debra, Adunyah, Samuel E, Albertson-Junkans, Ladia, Almoguera, Berta, Ames, Darren C, Appelbaum, Paul, Aronson, Samuel, Aufox, Sharon, Babb, Lawrence J, Balasubramanian, Adithya, Bangash, Hana, Basford, Melissa, Bastarache, Lisa, Baxter, Samantha, Behr, Meckenzie, Benoit, Barbara, Bhoj, Elizabeth, Bielinski, Suzette J, Bland, Sarah T, Blout, Carrie, Borthwick, Kenneth, Bottinger, Erwin P, Bowser, Mark, Brand, Harrison, Brilliant, Murray, Brodeur, Wendy, Caraballo, Pedro, Carrell, David, Carroll, Andrew, Castillo, Lisa, Castro, Victor, Chandanavelli, Gauthami, Chiang, Theodore, Chisholm, Rex L, Christensen, Kurt D, Chung, Wendy, Chute, Christopher G, City, Brittany, Cobb, Beth L, Connolly, John J, Crane, Paul, Crew, Katherine, Crosslin, David R, Dayal, Jyoti, De Andrade, Mariza, De la Cruz, Jessica, Denny, Josh C, Denson, Shawn, DeSmet, Tim, Dikilitas, Ozan, Dinsmore, Michael J, Dodge, Sheila, Dunlea, Phil, Edwards, Todd L, Eng, Christine M, Fasel, David, Fedotov, Alex, Feng, Qiping, Fleharty, Mark, Foster, Andrea, Freimuth, Robert, Friedrich, Christopher, Fullerton, Stephanie M, Funke, Birgit, Gabriel, Stacey, Gainer, Vivian, Gharavi, Ali, Gibbs, Richard A, Glazer, Andrew M, Glessner, Joseph T, Goehringer, Jessica, Gordon, Adam S, Graham, Chet, Green, Robert C, Gundelach, Justin H, Hain, Heather S, Hakonarson, Hakon, Harden, Maegan V, Harley, John, Harr, Margaret, Hartzler, Andrea, Hayes, M Geoffrey, Hebbring, Scott, Henrikson, Nora, Hershey, Andrew, Hoell, Christin, Holm, Ingrid, Howell, Kayla M, Hripcsak, George, Hu, Jianhong, Hynes, Elizabeth Duffy, Jarvik, Gail P, Jayaseelan, Joy C, Jiang, Yunyun, Joo, Yoonjung Yoonie, Jose, Sheethal, Josyula, Navya Shilpa, Justice, Anne E, Kalra, Divya, Karlson, Elizabeth W, Keating, Brendan J, Kelly, Melissa A, Kenny, Eimear E, Key, Dustin, Kiryluk, Krzysztof, Kitchner, Terrie, Klanderman, Barbara, Klee, Eric, Kochan, David C, Korchina, Viktoriya, Kottyan, Leah, Kudalkar, Emily, Rahm, Alanna Kulchak, Kullo, Iftikhar J, Lammers, Philip, Larson, Eric B, Lebo, Matthew S, Leduc, Magalie, Lee, Ming Ta, Lennon, Niall J, Leppig, Kathleen A, Leslie, Nancy D, Li, Rongling, Liang, Wayne H, Lin, Chiao-Feng, Linder, Jodell E, Lindor, Noralane M, Lingren, Todd, Linneman, James G, Liu, Cong, Liu, Wen, Liu, Xiuping, Lynch, John, Lyon, Hayley, Macbeth, Alyssa, Mahadeshwar, Harshad, Mahanta, Lisa, Malin, Bradley, Manolio, Teri, Marasa, Maddalena, Marsolo, Keith, McGowan, Michelle L, McNally, Elizabeth, Meldrim, Jim, Mentch, Frank, Rasouly, Hila Milo, Mosley, Jonathan, Mukherjee, Shubhabrata, Mullen, Thomas E, Muniz, Jesse, Murdock, David R, Murphy, Shawn, Murugan, Mullai, Muzny, Donna, Myers, Melanie F, Namjou, Bahram, Ni, Yizhao, Onofrio, Robert C, Obeng, Aniwaa Owusu, Person, Thomas N, Peterson, Josh F, Petukhova, Lynn, Pisieczko, Cassandra J, Pratap, Siddharth, Prows, Cynthia A, Puckelwartz, Megan J, Raj, Ritika, Ralston, James D, Ramaprasan, Arvind, Ramirez, Andrea, Rasmussen, Luke, Rasmussen-Torvik, Laura, Raychaudhuri, Soumya, Rehm, Heidi L, Ritchie, Marylyn D, Rives, Catherine, Riza, Beenish, Roden, Dan M, Rosenthal, Elisabeth A, Santani, Avni, Dan, Schaid, Scherer, Steven, Scott, Stuart, Scrol, Aaron, Sengupta, Soumitra, Shang, Ning, Sharma, Himanshu, Sharp, Richard R, Singh, Rajbir, Sleiman, Patrick M A, Slowik, Kara, Smith, Joshua C, Smith, Maureen E, Smoot, Duane T, Smoller, Jordan W, Sohn, Sunghwan, Stanaway, Ian B, Starren, Justin, Stroud, Mary, Su, Jessica, Taylor, Casey Overby, Tolwinski, Kasia, Van Driest, Sara L, Vargas, Sean M, Varugheese, Matthew, Veenstra, David, Venner, Eric, Verbitsky, Miguel, Vicente, Gina, Wagner, Michael, Walker, Kimberly, Walunas, Theresa, Wang, Liwen, Wang, Qiaoyan, Wei, Wei-Qi, Weiss, Scott T, Wells, Quinn S, Weng, Chunhua, White, Peter S, Wiesner, Georgia L, Wiley, Ken L, Williams, Janet L, Williams, Marc S, Wilson, Michael W, Witkowski, Leora, Woods, Laura Allison, Woolf, Betty, Wynn, Julia, Yang, Yaping, Zhang, Ge, Zhang, Lan, Zouk, Hana Neptune an environment for the delivery of genomic medicine 2021 Oct;23(10):1838-46. doi: doi.org/10.1038/s41436-021-01230-w. Epub 2021-07-13. PubMed

 

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