Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
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Lee H, Cashin A, Lamb SE, Hopewell S, Vansteelandt S, VanderWeele TJ, Lee H, Cashin AG, Lamb SE, Hopewell S, Vansteelandt S, VanderWeele TJ, MacKinnon DP, Mansell G, Collins GS, Golub RM, McAuley JH; AGReMA group, Localio AR, van Amelsvoort L, Guallar E, Rijnhart J, Goldsmith K, Fairchild AJ, Lewis CC, Kamper SJ, Williams CM, Henschke N. A guideline for reporting mediation analyses of randomized trials and observational studies: the AGReMA statement. JAMA. 2021 Sep 21;326(11):1045-1056. doi: 10.1001/jama.2021.14075. PubMed
Gold LS, Marcum ZA, Meier EN, Turner JA, James KT, Kallmes DF, Leutmer PH, Griffith B, Sherman KJ, Friedly JL, Suri P, Deyo RA, Johnson SK, Avins AL, Heagerty PJ, Jarvik JG. Patient, provider, and clinic characteristics associated with opioid and non-opioid pain medication prescriptions for patients receiving low back imaging in primary care. J Am Board Fam Med. 2021 Sep-Oct;34(5):950-963. doi: 10.3122/jabfm.2021.05.210033. PubMed
Peskoe SB, Arterburn D, Coleman KJ, Herrinton LJ, Daniels MJ, Haneuse S. Adjusting for selection bias due to missing data in electronic health records-based research. Stat Methods Med Res. 2021 Oct;30(10):2221-2238. doi: 10.1177/09622802211027601. Epub 2021 Aug 26. PubMed
Qian T, Yoo H, Klasnja P, Almirall D, Murphy SA. Rejoinder: 'estimating time-varying causal excursion effects in mobile health with binary outcomes'. Biometrika. 2021 Aug 12;108(3):551-555. doi: 10.1093/biomet/asab033. eCollection 2021. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |