Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Sinaiko AD, Landrum MB, Meyers DJ, Alidina S, Maeng DD, Friedberg MW, Kern LM, Edwards AM, Flieger SP, Houck PR, Peele P, Reid RJ, McGraves-Lloyd K, Finison K, Rosenthal MB Synthesis Of Research On Patient-Centered Medical Homes Brings Systematic Differences Into Relief 2017 Mar;36(3):500-508. doi: 10.1377/hlthaff.2016.1235. PubMed
Daley MF, Newton DA, DeBar L, Newcomer SR, Pieper L, Boscarino JA, Toh S, Pawloski P, Nordin JD, Nakasato C, Herrinton LJ, Bussing R. Accuracy of electronic health record-derived data for the identification of incident ADHD. J Atten Disord. 2017 Mar;21(5):416-425. doi: 10.1177/1087054713520616. Epub 2014 Jan 1. PubMed
Almoguera B, Vazquez L, Mentch F, Connolly J, Pacheco JA, Sundaresan AS, Peissig PL, Linneman JG, McCarty CA, Crosslin D, Carrell DS, Lingren T, Namjou-Khales B, Harley JB, Larson E, Jarvik GP, Brilliant M, Williams MS, Kullo IJ, Hysinger EB, Sleiman PM, Hakonarson H. Identification of four novel loci in asthma in European American and African American populations. Am J Respir Crit Care Med. 2017;195(4):456-463. doi: 10.1164/rccm.201604-0861OC. PubMed
Keith RE, Crosson JC, O'Malley AS, Cromp D, Taylor EF Using the Consolidated Framework for Implementation Research (CFIR) to produce actionable findings: a rapid-cycle evaluation approach to improving implementation 2017 Feb 10;12(1):15. doi: 10.1186/s13012-017-0550-7. Epub 2017-02-10. PubMed
Hanuese S, Shortreed SM. On the use of electronic health records for comparative effectiveness research. In: Gatsonis C, Morton SC, editors. Methods for Comparative effectiveness research. CRC Press PubMed
Claire Allen, MPHManager, Collaborative Science |
Katharine A. Bradley, MD, MPHSenior Investigator |
Yates Coley, PhDAssociate Biostatistics Investigator |
Beverly B. Green, MD, MPHSenior Investigator |
Annie Hoopes, MD, MPHAssistant Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
James D. Ralston, MD, MPHSenior Investigator |
Brian D. Williamson, PhDAssociate Biostatistics Investigator |