Yates Coley, PhD, is a biostatistician whose research promotes predictive analytics and learning health systems as a way to improve value quality, and equity in health care delivery. Their statistical research focuses on developing clinical prediction models that are accurate, actionable, and fair. This work spans several statistical domains including repeated measurements, missing data, and machine learning.
Dr. Coley’s paper examining racial and ethnic inequity in two suicide prediction models was awarded Paper of the Year at the Healthcare Systems Research Network 2021 Annual Conference. The two models performed well for visits by patients who were White, Hispanic, and Asian but did not accurately identify high-risk visits for patients who were Black, American Indian, and Alaskan Native, likely due to persistent structural barriers limiting access to affordable, high-quality, and culturally competent mental health care. The study emphasized the importance of assessing performance within racial and ethnic subgroups of all prediction models before clinical implementation to ensure that prediction models ameliorate, rather than exacerbate, existing health disparities.
Dr. Coley is a graduate of the CATALyST K12 Washington Learning Health System Program funded by the Agency for Healthcare Research and Quality and the Patient-Centered Outcomes Research Institute. As part of their training in learning health system research, Dr. Coley studied current barriers to implementing evidence-based predictive analytics tools to help develop prediction tools that can be deployed and sustained in clinical care. Their research plan also focused on statistical methods to address racial bias in clinical prediction algorithms.
Before starting as an assistant investigator at Kaiser Permanente Washington Health Research Institute (KPWHRI) in 2016, Dr. Coley was a postdoctoral research fellow at Johns Hopkins Bloomberg School of Public Health. There, they worked with urologists to develop a prediction model that enables personalized management of low-risk prostate cancer.
Dr. Coley completed their PhD in biostatistics at the University of Washington. Their dissertation research proposed methods to improve effectiveness estimates in HIV prevention trials by accounting for unobserved variability in risk.
At KPWHRI, Dr. Coley collaborates on projects across a range of research areas including mental health, breast cancer imaging, aging, and health services. They also lead predictive analytics work and direct biostatistical support for KPWHRI’s Center for Accelerating Care Transformation.
Bayesian analysis, causal inference, data visualization, hierarchical models, longitudinal data analysis, missing data, prediction, survival analysis
Suicide risk, depression treatment, measurement-based care, antipsychotic use in adolescents
Biostatistics, prostate cancer, risk stratification, stakeholder engagement, surveillance
Biostatistics, data visualization, interactive decision-support tools, learning health systems, stakeholder engagement
Biostatistics, clinical decision-support, learning health systems, patient-centeredness, shared decision-making, stakeholder engagement
Simon GE, Shortreed SM, Coley RY, Penfold RB, Rossom RC, Waitzfelder BE, Sanchez K, Lynch FL Assessing and Minimizing Re-identification Risk in Research Data Derived from Health Care Records 2019 Mar 29;7(1):6. doi: 10.5334/egems.270. Epub 2019-03-29. PubMed
Arterburn D, Wellman R, Emiliano A, Smith SR, Odegaard AO, Murali S, Williams N, Coleman KJ, Courcoulas A, Coley RY, Anau J, Pardee R, Toh S, Janning C, Cook A, Sturtevant J, Horgan C, McTigue KM, PCORnet Bariatric Study Collaborative Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss: A PCORnet Cohort Study 2018 Dec 4;169(11):741-750. doi: 10.7326/M17-2786. Epub 2018-10-30. PubMed
Huntley JH, Coley RY, Carter HB, Radhakrishnan A, Krakow M, Pollack CE Clinical evaluation of an individualized risk prediction tool for men on active surveillance for prostate cancer 2018 Nov;121:118-124. doi: 10.1016/j.urology.2018.08.021. Epub 2018-08-30. PubMed
Inge TH, Coley RY, Bazzano LA, Xanthakos SA, McTigue K, Arterburn D, Williams N, Wellman R, Coleman KJ, Courcoulas A, Desai NK, Anau J, Pardee R, Toh S, Janning C, Cook A, Sturtevant J, Horgan C, Zebrick AJ, Michalsky M, PCORnet Bariatric Study Collaborative Comparative effectiveness of bariatric procedures among adolescents: the PCORnet bariatric study 2018 Sep;14(9):1374-1386. doi: 10.1016/j.soard.2018.04.002. Epub 2018-04-17. PubMed
Toh S, Wellman R, Coley RY, Horgan C, Sturtevant J, Moyneur E, Janning C, Pardee R, Coleman KJ, Arterburn D, McTigue K, Anau J, Cook AJ Combining distributed regression and propensity scores: a doubly privacy-protecting analytic method for multicenter research 2018 Jan;10:1773-1786. doi: 10.2147/CLEP.S178163. Epub 2018-11-27. PubMed
Paper describes a novel predictive model that identifies patients at high risk of hospitalization or death.
New risk model uses advanced analytics to guide informed treatment decisions at Kaiser Permanente Washington.
Their work contributes to improved quality of care and better understanding of patients’ needs.
A new study aims to understand trends in digital care communication among teens.
JSM TV, Aug. 6, 2024