Heart disease is the leading cause of death for Americans. Kaiser Permanente Washington Health Research Institute (KPWHRI) scientists are working to understand how to reduce our risk of heart attacks, stroke, and other cardiovascular diseases throughout life.
Addressing risk factors, improving diagnosis, and exploring how medications, genes, and everyday life affect our cardiovascular health at different ages and stages are central to this work — as is translating research findings into practical, personalized care.
“We’ve found that helping patients and health care teams work together on personalized care plans is the best path to lifelong heart health,” says Beverly Green, MD, MPH, whose recent work has focused on improving the diagnosis of high blood pressure.
Additional focus areas for KPWHRI scientists include exploring the impact of cardiovascular diseases on other health conditions — and vice versa. Recently, this has led researchers Sascha Dublin, MD, PhD, and Laura B. Harrington, PhD, MPH, to investigate the impact of COVID-19 on cardiovascular health.
Below are other research highlights from KPWHRI’s cardiovascular health scientists (please visit their bios to learn more):
Green BB, Anderson ML, Ehrlich K, Hall YN, Hansell LD, Hsu C, Joseph D, Margolis KL, McClure JB, Munson SA, Thompson MJ. Blood pressure checks for diagnosing hypertension: Health professionals’ knowledge, beliefs, and practices. J Am Board Fam Med. 2022 Mar-Apr;35(2):310-319. doi: 10.3122/jabfm.2022.02.210318. PubMed
Stacey D, Chen L, Stanczyk PJ, Howson JMM, Mason AM, Burgess S, MacDonald S, Langdown J, McKinney H, Downes K, Farahi N, Peters JE, Basu S, Pankow JS, Tang W, Pankratz N, Sabater-Lleal M, de Vries PS, Smith NL; CHARGE Hemostasis Working Group, Gelinas AD, Schneider DJ, Janjic N, Samani NJ, Ye S, Summers C, Chilvers ER, Danesh J, Paul DS. Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus. Nat Commun. 2022 Mar 9;13(1):1222. doi: 10.1038/s41467-022-28729-3. Erratum in: Nat Commun. 2022 Apr 6;13(1):1962. PubMed
Green BB, Anderson ML, Cook AJ, Ehrlich K, Hall YN, Margolis KL, Thompson MJ. Automated office blood pressure and the impact of attendance and rest on diagnostic accuracy. Am J Hypertens. 2022 Jul 1;35(7):638-646. doi: 10.1093/ajh/hpac032. PubMed
Green BB, Anderson ML, Cook AJ, Ehrlich K, Hall YN, Hsu C, Joseph D, Klasnja P, Margolis KL, McClure JB, Munson SA, Thompson MJ. Clinic, home, and kiosk blood pressure measurements for diagnosing hypertension: a randomized diagnostic study. J Gen Intern Med. 2022 Mar 3. doi: 10.1007/s11606-022-07400-z. [Epub ahead of print]. PubMed
Roden D, Glazer AM, Davogustto GE, Yang T, Muhammad A, Mosley JD, Larson EB, Van Driest S, Wells QS, Wada Y, Bland S, Yoneda ZT, Kroncke BM, George A, Shoemaker MB. Arrhythmia variant associations and reclassifications in the eMERGE-III sequencing study. Circulation. 2021 Dec 21. doi: 10.1161/CIRCULATIONAHA.121.055562. Online ahead of print. PubMed
Sascha Dublin, MD, PhDSenior Investigator |
Beverly B. Green, MD, MPHSenior Investigator |
Laura Harrington, PhD, MPHAssistant Investigator |
Ellen O'Meara, PhDPrincipal Collaborative Scientist |
Nicole M. Gatto, PhD, MPHPrincipal Collaborative Scientist |
Meagan C. Brown, PhD, MPHAssistant Investigator |
James Floyd, MD, MS
Assistant Professor, Department of Medicine
Adjunct Assistant Professor, Department of Epidemiology
University of Washington
Susan Heckbert, MD, PhD
University of Washington (UW) Department of Epidemiology; UW Cardiovascular Health Research Unit
Nicholas L. Smith, PhD, MPH
UW Professor, Epidemiology, Cardiovascular Health Research Unit
Director, Seattle Epidemiology and Information Resource Center, VA Puget Sound Health Care System