Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Silverberg M, Leyden W, Stewart C, Ralston J, Horberg M, Carzasty S, Grothaus L, Catz S. Change in adherence to antiretrovirals after initial use of an electronic shared medical record among HIV-infected individuals. Clin Med Res. 2012;10(3):144-5. PubMed
Grafton J, Ott S, Endres J, Kratohvil C, Hubbard R, Ichikawa L, St John J, Operskalski B, Spangler L, Anderson J, Rillamas-Sun E, LaCroix A, Scholes D. Ps1-52: Charting the course: adjudicating fractures in network enrollees using the electronic medical record. Clin Med Res. 2012;10(3):165. PubMed
Hotaling JM, Walsh TJ, Macleod LC, Heckbert S, Pocobelli G, Wessells H, White E. Erectile dysfunction is not independently associated with cardiovascular death: data from the vitamins and lifestyle (VITAL) study. J Sex Med. 2012 Aug;9(8):2104-10. doi: 10.1111/j.1743-6109.2012.02826.x. Epub 2012 Jul 3. PubMed
Chubak J, Yu O, Pocobelli G, Lamerato L, Webster J, Prout MN, Ulcickas Yood M, Barlow WE, Buist DS. Administrative data algorithms to identify second breast cancer events following early-stage invasive breast cancer. J Natl Cancer Inst. 2012 Jun 20;104(12):931-40. Epub 2012 Apr 30. PubMed
Allen LA, Yood MU, Wagner EH, Aiello Bowles EJ, Pardee R, Wellman R, Habel L, Nekhlyudov L, Davis RL, Onitilo AA, Magid DJ; for the Pharmacovigilance Research Group. Performance of claims-based algorithms for identifying heart failure and cardiomyopathy among patients diagnosed with breast cancer. Med Care. 2014 May;52(5):e30-8. doi: 10.1097/MLR.0b013e31825a8c22. Epub 2012 May 25. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |