Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Jackson KL, Mbagwu M, Pacheco JA, Baldridge AS, Viox DJ, Linneman JG, Shukla SK, Peissig PL, Borthwick KM, Carrell DA, Bielinski SJ, Kirby JC, Denny JC, Mentch FD, Vazquez LM, Rasmussen-Torvik LJ, Kho AN. Performance of an electronic health record-based phenotype algorithm to identify community associated methicillin-resistant Staphylococcus aureus cases and controls for genetic association studies. BMC Infect Dis. 2016 Nov 17;16(1):684. PubMed
Hansen RN, Walker RL, Shortreed SM, Dublin S, Saunders K, Ludman EJ, Von Korff M. Impact of an opioid risk reduction initiative on motor vehicle crash risk among chronic opioid therapy patients. Pharmacoepidemiol Drug Saf. 2016 Nov 14. doi: 10.1002/pds.4130. [Epub ahead of print]. PubMed
Floyd JS, Wellman R, Fuller S, Bansal N, Psaty BM, de Boer IH, Scholes D. Use of electronic health data to estimate heart failure events in a population-based cohort with CKD. Clin J Am Soc Nephrol. 2016 Nov 7;11(11):1954-1961. Epub 2016 Aug 9. PubMed
Park A, Hartzler AL, Huh J, Hsieh G, McDonald DW, Pratt W. "How did we get here?": topic drift in online health discussions. J Med Internet Res. 2016 Nov 2;18(11):e284. PubMed
Asche SE, O'Connor PJ, Dehmer SP, Green BB, Bergdall AR, Maciosek MV, Nyboer RA, Pawloski PA, Sperl-Hillen JM, Trower NK, Margolis KL. Patient characteristics associated with greater blood pressure control in a randomized trial of home blood pressure telemonitoring and pharmacist management. J Am Soc Hypertens. 2016 Nov;10(11):873-880. doi: 10.1016/j.jash.2016.09.004. Epub 2016 Sep 25. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |