Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Veenstra DL, Guzauskas GF, Villa KF, Boudreau DM. The budget impact and cost-effectiveness of defibrotide for treatment of veno-occlusive disease with multi-organ dysfunction in patients post-hematopoietic stem cell transplant. J Med Econ. 2017 Jan 7:1-11. doi: 10.1080/13696998.2016.1275652. [Epub ahead of print]. PubMed
Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, Riess H, Sivapalaratnam S, Tragante V, van Iperen EPA, Brautbar A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Larson EB, Rasmussen-Torvik LJ, Tromp G, Baumert J, Cruickshanks KJ, Farrall M, Hingorani AD, Hovingh GK, Kleber ME, Klein BE, Klein R, Koenig W, Lange LA, M?rz W, North KE, Charlotte Onland-Moret N, Reiner AP, Talmud PJ, van der Schouw YT, Wilson JG, Kivimaki M, Kumari M, Moore JH, Drenos F, Asselbergs FW, Keating BJ, Ritchie MD Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals 2017 Jan;10:25. doi: 10.1186/s13040-017-0145-5. Epub 2017-07-24. PubMed
Tuzzio L, Ludman EJ, Chang E, Palazzo L, Abbott T, Wagner EH, Reid RJ Design and Implementation of a Physician Coaching Pilot to Promote Value-Based Referrals to Specialty Care 2017 Jan;21. doi: 10.7812/TPP/16-066. PubMed
Bettcher BM, Ard MC, Reed BR, Benitez A, Simmons A, Larson EB, Sonnen JA, Montine TJ, Li G, Keene CD, Crane PK, Mungas D Association between Cholesterol Exposure and Neuropathological Findings: The ACT Study 2017 Jan;59(4):1307-1315. doi: 10.3233/JAD-161224. PubMed
Kim JG, Rodriguez HP, Estlin KA, Morris CG Impact of Longitudinal Electronic Health Record Training for Residents Preparing for Practice in Patient-Centered Medical Homes 2017 Jan;21. doi: 10.7812/TPP/16-122. PubMed
Claire Allen, MPHManager, Collaborative Science |
Katharine A. Bradley, MD, MPHSenior Investigator |
Yates Coley, PhDAssociate Biostatistics Investigator |
Beverly B. Green, MD, MPHSenior Investigator |
Annie Hoopes, MD, MPHAssistant Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
James D. Ralston, MD, MPHSenior Investigator |
Brian D. Williamson, PhDAssociate Biostatistics Investigator |