Research is often lauded for finding life-saving treatments for diseases like cancer or diabetes. But consider the impact of preventing such illnesses from developing in the first place. It’s hard to describe the value of stopping illness or injury from happening. Yet that’s the goal of research on preventive care.
Most Kaiser Permanente Washington scientists study prevention, whether their work focuses on promoting health by influencing individual behavior, building sound prevention services into everyday clinical care, designing smart health coverage, or all three. By conducting their research at Kaiser Permanente Washington—which combines care and coverage—our researchers have access to data from a large, stable population over time, allowing them to discover which approaches to prevention work best.
Examples include research in areas such as:
A team of researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) produces reviews of scientific evidence that policymakers at the Centers for Medicare & Medicaid Services and the U.S. Preventive Services Task Force and others use in health care decision-making. We do this work as part of the Kaiser Permanente Research Affiliates Evidence-based Practice Center, one of 13 centers nationwide that are sponsored by the federal Agency for Healthcare Research and Quality.
We’re improving the safety and effectiveness of vaccines through clinical trials, and we’re monitoring how well each year’s new flu vaccines are working. In addition, we’re studying ways to better inform parents about the benefits and potential harms of childhood vaccines, to improve their uptake.
We’re working on several fronts to help ensure the safety of prescription drugs and other medical treatments. For example, we play a leading role in the Food and Drug Administration’s Sentinel program to monitor the safety of medical products through routinely collected electronic health care data. We’re exploring ways to improve the safety of prescribing opioid pain medications. And we often study the safety of drugs commonly used to prevent chronic conditions like heart disease, cancer, and depression.
Prevention also includes screening to detect disease before symptoms appear, to identify and treat disease at an earlier stage. Our research is improving the effectiveness of cancer screening programs so people get the appropriate tests when needed based on their particular risks. Our research is also aimed at improving clinical screening for behavioral risks such as smoking, suicidal thoughts, alcohol use disorders, and poor eating and exercise habits.
Our research in areas such as smoking cessation, healthy diet, and chronic illness care finds new ways to encourage individuals to adopt and maintain healthier lifestyles. At the same time, we’re exploring ways to reach large populations through the use of phone-based programs, websites, and mobile technologies.
Chen AT, Wang LC, Pike KC, Conway M, Glass JE Comparing the Use Experiences, Contextual Factors, and Recovery Strategies Associated with Different Substances: An Analysis of Social Media Narratives 2025 Aug 5;60(14):2287-2298 doi:10.1080/10826084.2025.2540938. doi: 10.1080/10826084.2025.2540938. Epub 2025-08-05. PubMed
Wolpaw BJ, Oren H, Quinnan-Hostein L, Bradley KA, Johnson NJ, Hallgren KA, Gupta A, Kim HN, Granich MA, Steel TL Hospital-Wide Implementation, Clinical Outcomes, and Safety of Phenobarbital for Alcohol Withdrawal 2025 Aug;8(8):e2528694. doi: 10.1001/jamanetworkopen.2025.28694. Epub 2025-08-01. PubMed
Simon CB, Matson TE, Oliver M, Hallgren KA, Weiss RD, Bradley KA Primary Care Patients With Opioid Use Disorder Symptoms: Initiation and Engagement in Treatment With Medicine 2025 Jul 28;23(4):308-314. doi: 10.1370/afm.240440. Epub 2025-07-28. PubMed
DeBar LL, Mayhew M, Wellman RD, Balderson BH, Dickerson JF, Elder CR, Justice M, Keefe FJ, McMullen CK, Owen-Smith AA, Rini C, Von Korff M, Waring S, Yarava A, Shen Z, Thompson RE, Clark AE, Casper TC, Cook AJ Telehealth and Online Cognitive Behavioral Therapy-Based Treatments for High-Impact Chronic Pain: A Randomized Clinical Trial 2025 Jul 23 doi: 10.1001/jama.2025.11178. Epub 2025-07-23. PubMed
Hamilton LK, Lapham GT, Day A, Black-Watson M, Bishop D, Parsons D, Budimir CA, Baulckim L, Lee AK, Addis M, Bradley KA Improving alcohol-related care in small-medium primary care practices: An evaluation of an adaptation of the SPARC trial intervention for small-medium sized practices 2025 Jun;173:209697. doi: 10.1016/j.josat.2025.209697. Epub 2025-04-12. PubMed
Julie Angerhofer, PhD, MPHAssociate Investigator |
Jennifer F. Bobb, PhDSenior Biostatistics Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Clarissa Hsu, PhDAssociate Investigator |
Noorie Hyun, PhDAssociate Biostatistics Investigator |
Morgan Justice, PhD, MASenior Collaborative Scientist |
Gwen Lapham, PhD, MPH, MSWAssociate Investigator |
Theresa E. Matson, PhD, MPHCollaborative Scientist |
Jess Mogk, MPHCollaborative Scientist |
Yu-Ru Su, PhDAssociate Biostatistics Investigator |
Paige D. Wartko, PhD, MPHSenior Collaborative Scientist |