Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Yeung K. Value-based insurance design: current evidence and future directions. J Manag Care Spec Pharm. 2019 Jul;25(7):738-741. doi: 10.18553/jmcp.2019.25.7.738. PubMed
Seewald NJ, Smith SN, Lee AJ, Klasnja P, Murphy SA. Practical considerations for data collection and management in mobile health micro-randomized trials. Stat Biosci. 2019;11(2):355-370. doi: 10.1007/s12561-018-09228-w. Epub 2019 Jan 5. PubMed
Hazlehurst B, Green CA, Perrin NA, Brandes J, Carrell DS, Baer A, DeVeaugh-Geiss A, Coplan PM. Using natural language processing of clinical text to enhance identification of opioid-related overdoses in electronic health records data. Pharmacoepidemiol Drug Saf. 2019 Jun 19. doi: 10.1002/pds.4810. [Epub ahead of print]. PubMed
Augustine MR, Nelson KM, Fihn SD, Wong ES. Patient-reported access in the patient-centered medical home and avoidable hospitalizations: an observational analysis of the Veterans Health Administration. J Gen Intern Med. 2019 Jun 3. pii: 10.1007/s11606-019-05060-0. doi: 10.1007/s11606-019-05060-0. [Epub ahead of print]. PubMed
Henrikson NB, Blasi PR, Corsmo JJ, Sheffer Serdoz E, Scrol A, Greene SM, Matthews TL, Ralston JD. "You really do have to know the local context": IRB administrators and researchers on the implications of the NIH Single IRB mandate for multisite genomic studies. J Empir Res Hum Res Ethics. 2019 Jul;14(3):286-295. doi: 10.1177/1556264619850440. Epub 2019 May 22. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |