Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Hubbard R, Johnson E, Chubak J, Wernli KJ, Kamineni A, Bogart A, Rutter C. Estimating screening test effectiveness when screening indication is unknown using generalized linear finite mixture models. Health Services Outcomes Res Methodol.2017 17(2):101-112.
Eschler J, Meas PL, Lozano P, McClure JB, Ralston JD, Pratt W. Integrating the patient portal into the health management work ecosystem: user acceptance of a novel prototype. AMIA Annu Symp Proc. 2017 Feb 10;2016:541-550. eCollection 2016. PubMed
O’Leary KO, Liu L, McClure JB, Ralston J, Pratt W. Persuasive reminders for health self-management. AMIA Annu Symp Proc. 2017 Feb 10;2016:994-1003. eCollection 2016. PubMed
Smith-Bindman R, Wang Y, Yellen-Nelson TR, Moghadassi M, Wilson N, Gould R, Seibert A, Boone JM, Krishnam M, Lamba R, Hall DJ, Miglioretti DL. Predictors of CT radiation dose and their effect on patient care: a comprehensive analysis using automated data. Radiology. 2017 Jan;282(1):182-193. doi: 10.1148/radiol.2016151391. Epub 2016 Jul 20. PubMed
Carrell DS, Cronkite DJ, Malin BA, Aberdeen JS, Hirschman L. Is the juice worth the squeeze? costs and benefits of multiple human annotators for clinical text de-identification. Methods Inf Med. 2016 Aug 5;55(4):356-64. doi: 10.3414/ME15-01-0122. Epub 2016 Jul 13. PubMed
![]() James D. Ralston, MD, MPHSenior Investigator |
![]() Jennifer B. McClure, PhDDirector, Investigative Science |
![]() Beverly B. Green, MD, MPHSenior Investigator |
![]() Katharine A. Bradley, MD, MPHSenior Investigator |
![]() Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
![]() Yates Coley, PhDAssociate Biostatistics Investigator |
![]() Brian D. Williamson, PhDAssistant Biostatistics Investigator |
![]() Annie Hoopes, MD, MPHActing Assistant Investigator |
![]() Claire Allen, MPHManager, Collaborative Science |
![]() Annie Piccorelli, PhDSenior Collaborative Biostatistician |