Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Carrell DS, Halgrim S, Tran DT, Buist DS, Chubak J, Chapman WW, Savova G. Using natural language processing to improve efficiency of manual chart abstraction in research: the case of breast cancer recurrence. Am J Epidemiol. 2014 Mar 15;179(6):749-58. doi: 10.1093/aje/kwt441. Epub 2014 Jan 30. PubMed
Heller J, Givens ML, Yuen TK, Gould S, Jandu MB, Bourcier E, Choi T. Advancing efforts to achieve health equity: equity metrics for health impact assessment practice. Int J Environ Res Public Health. 2014 Oct 24;11(11):11054-64. doi: 10.3390/ijerph111111054. PubMed
Coronado GD, Burdick T, Kapka T, Retecki S, Green BB. Using an automated data-driven EHR-embedded program for mailing FIT kits: lessons from the STOP CRC pilot study. J Gen Pract (Los Angel). 2014 Jan 5;2. pii: 1000141.
Nelson JC, Shortreed SM, Yu O, Peterson D, Baxter R, Fireman B, Lewis N, McClure D, Weintraub E, Xu S, Jackson LA. Integrating database knowledge and epidemiological design to improve the implementation of data mining methods to evaluate vaccine safety in large healthcare databases. Stat Anal Data Min. 2014;7(5):33751.
Lanham HJ, Sittig DF, Leykum LK, Parchman ML, Pugh JA, McDaniel RR. Understanding differences in electronic health record (EHR) use: linking individual physicians' perceptions of uncertainty and EHR use patterns in ambulatory care. J Am Med Inform Assoc. 2014 Jan 1;21(1):73-81. doi:10.1136/amiajnl-2012-001377. Epub 2013 May 22. PubMed
![]() James D. Ralston, MD, MPHSenior Investigator |
![]() Jennifer B. McClure, PhDDirector, Investigative Science |
![]() Beverly B. Green, MD, MPHSenior Investigator |
![]() Katharine A. Bradley, MD, MPHSenior Investigator |
![]() Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
![]() Yates Coley, PhDAssociate Biostatistics Investigator |
![]() Brian D. Williamson, PhDAssistant Biostatistics Investigator |
![]() Annie Hoopes, MD, MPHActing Assistant Investigator |
![]() Claire Allen, MPHManager, Collaborative Science |
![]() Annie Piccorelli, PhDSenior Collaborative Biostatistician |