Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Shortreed SM, Rutter CM, Cook AJ, Simon GE. Improving pragmatic clinical trial design using real-world data. Clin Trials. 2019 Jun;16(3):273-282. doi: 10.1177/1740774519833679. Epub 2019 Mar 13. PubMed
Henrikson NB, Blasi PR, Fullerton SM, Grafton J, Leppig KA, Jarvik GP, Larson EB. "It would be so much easier": health system-led genetic risk notification-feasibility and acceptability of cascade screening in an integrated system. J Community Genet. 2019 Mar 6. pii: 10.1007/s12687-019-00412-z. doi: 10.1007/s12687-019-00412-z. [Epub ahead of print]. PubMed
Hsu C, Gray MF, Murray L, Abraham M, Nickel W, Sweeney JM, Frosch DL, Mroz TM, Ehrlich K, Johnson B, Reid RJ. Actions and processes that patients, family members, and physicians associate with patient- and family-centered care. BMC Fam Pract. 2019 Feb 25;20(1):35. doi: 10.1186/s12875-019-0918-7. PubMed
Karter AJ, Warton EM, Moffet HH, Ralston JD, Huang ES, Miller DR, Lipska KJ. Revalidation of the hypoglycemia risk stratification tool using ICD-10 codes. Diabetes Care. 2019 Feb 14. pii: dc18-2154. doi: 10.2337/dc18-2154. [Epub ahead of print]. PubMed
Bradley R, Booth-LaForce C, Hanes D, Scott C, Sherman KJ, Lin YS, Zwickey H. Design of a multidisciplinary training program in complementary and integrative health clinical research: building research across interdisciplinary gaps. J Altern Complement Med. 2019; 25: 509-16. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |