Mental Health

“We aim to be a real learning mental health care system, answering the practical questions that patients, families, and mental health clinicians care about.”

Greg Simon, MD, MPH
Kaiser Permanente Washington Health Research Institute Senior Investigator

Research overview

Mental health is a vital part of overall health. But traditional mental health care reaches only a fraction of the millions who could benefit. So, researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) are finding practical, patient-centered ways to reach people affected by conditions such as depression, bipolar disorder, and anxiety.

“Many of the ideas that are changing American mental health care were first tested here at Kaiser Permanente Washington,” said Gregory Simon, MD, MPH, senior investigator at KPWHRI and a Kaiser Permanente Washington psychiatrist. “We’re now working to spread those innovations to large health systems across the country.”

Some of the mental health research group’s current projects include:

  • Conducting research to optimize firearm suicide prevention in health care
  • Developing methods to reduce racial and ethnic disparities in suicide risk prediction
  • Expanding a program to reduce the burden for caregivers of patients with a dementia diagnosis
  • Testing an intervention to guide earlier access to services for youth with symptoms or concerns related to their mental health
  • Reducing suicide attempts among high-risk teens and young adults
  • Testing interventions for variables associated with dementia risk, such as depression and social isolation, in elderly patients
  • Developing a model to predict risk of a psychosis spectrum disorder diagnosis
  • Improving tailoring of depression care using customized clinical decision support
  • Studying how peer support is being used to support youth mental health

Innovative patient-centered mental health programs developed at KPWHRI include:

  • Using collaborative care to integrate depression mental health care with general medical care
  • Developing flexible, patient-centered psychotherapy programs organized around people’s preferences and values and delivered online or by phone
  • Identifying and addressing racial and ethnic disparities in mental health treatment
  • Tailoring depression programs for people with other health conditions (diabetes, heart disease, obesity)
  • Using technology such as the web and secure email for outreach and care coordination
  • Facilitating earlier identification of people at risk for self-harm or suicide attempts
  • Improving physical health in people with severe mental health problems
  • Combining peer support with professional treatment for mood disorders
  • Broadening the focus of mental health treatment from symptom management to recovery
  • Activating mental health patients to be more knowledgeable and assertive
  • Reducing use of high-risk medications in both children and older adults
  • Collaborating with health systems through the national Mental Health Research Network to systematically measure and improve outcomes of care

“We are partnering with health care leaders at Kaiser Permanente Washington and other health systems to test innovative programs and implement treatments that work,” Simon said. “We want ‘learning health care system’ to be more than a slogan.” 

Recent publications on Mental Health

Ludman EJ, Simon GE. Coordinated multi-component treatment in primary care improves anxiety in adults with multiple anxiety disorders compared with usual care.  Evid Based Ment Health. 2010;13(4):121. PubMed

Simon GE, Rohde P, Ludman EJ, Jeffery RW, Linde JA, Operskalski BH, Arterburn D. Association between change in depression and change in weight among women enrolled in weight loss treatment.  Gen Hosp Psychiatry. 2010;32(6):583-9. Epub 2010 Oct 27. PubMed

Linde JA, Simon GE, Ludman EJ, Ichikawa LE, Operskalski BH, Arterburn D, Rohde P, Finch EA, Jeffery RW. A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression.  Ann Behav Med. 2011 Feb;41(1):119-30. Epub 2010 Sep 28. PubMed

Simon GE, Perlis RH. Personalized medicine for depression: can we match patients with treatments?  Am J Psychiatry. 2010 Dec;167(12):1445-55. Epub 2010 Sep 15. Review. PubMed

Williams LH, Rutter CM, Katon WJ, Reiber GE, Ciechanowski P, Heckbert SR, Lin EH, Ludman EJ, Oliver MM, Young BA, Von Korff M. Depression and incident diabetic foot ulcers: a prospective cohort study.  Am J Med. 2010;123(8):748-754.e3. PubMed

Researchers in Mental Health

Gregory E. Simon, MD, MPH

Senior Investigator
206-287-2979
Gregory.E.Simon@kp.org

Curriculum vitae (CV)

Ben Balderson, PhD

Senior Collaborative Scientist
206-287-2803
Benjamin.H.Balderson@kp.org

Curriculum vitae (CV)

Katharine A. Bradley, MD, MPH

Senior Investigator
206-287-2151
Katharine.A.Bradley@kp.org

Curriculum vitae (CV)

Paula Lozano, MD, MPH

Senior Investigator; Director, ACT Center
206-287-2113
Paula.Lozano@kp.org

Curriculum vitae (CV)

Jennifer B. McClure, PhD

Director, Investigative Science
206-287-2737
Jennifer.B.Mcclure@kp.org

Curriculum vitae (CV)

Robert Penfold, PhD

Senior Investigator
206-287-2232
Robert.B.Penfold@kp.org

Curriculum vitae (CV)

Susan M. Shortreed, PhD

Senior Biostatistics Investigator
206-287-2088
Susan.M.Shortreed@kp.org

Curriculum vitae (CV)

Dori E. Rosenberg, PhD, MPH

Senior Investigator
206-287-2532
Dori.E.Rosenberg@kp.org

Curriculum vitae (CV)

Gwen Lapham, PhD, MPH, MSW

Assistant Investigator
206-287-2021
Gwen.T.Lapham@kp.org

Curriculum vitae (CV)

Jennifer F. Bobb, PhD

Associate Biostatistics Investigator
206-287-2190
Jennifer.F.Bobb@kp.org

Curriculum vitae (CV)

Joseph E. Glass, PhD, MSW

Associate Investigator
206-287-4266
Joseph.E.Glass@kp.org

Curriculum vitae (CV)

Julie E. Richards, PhD, MPH

Assistant Investigator
206-287-2100
Julie.E.Richards@kp.org

Curriculum vitae (CV)

Paige D. Wartko, PhD, MPH

Senior Collaborative Scientist
206-442-5230
Paige.D.Wartko@kp.org

Curriculum vitae (CV)

Yates Coley, PhD

Associate Biostatistics Investigator
206-287-2071
Rebecca.Y.Coley@kp.org

Curriculum vitae (CV)

Abisola Idu, MS, MPH

Collaborative Biostatistician
206-287-2893
abisola.idu@kp.org

Curriculum vitae (CV)

Eric Johnson, MS

Senior Collaborative Biostatistician
206-287-2105
Eric.Johnson@kp.org

Curriculum vitae (CV)

Rod L. Walker, MS

Principal Collaborative Biostatistician
206-287-2895
Rod.L.Walker@kp.org

Curriculum vitae (CV)

Robert D. Wellman, MS

Principal Collaborative Biostatistician
206-287-2557
Robert.D.Wellman@kp.org

Curriculum vitae (CV)

Leah K. Hamilton, PhD

Senior Collaborative Scientist
206-287-2515
Leah.K.Hamilton@kp.org

Curriculum vitae (CV)

Brian D. Williamson, PhD

Assistant Biostatistics Investigator
206-287-2024
Brian.D.Williamson@kp.org

Curriculum vitae (CV)

Rosemary Meza, PhD, MS

Collaborative Scientist
Rosemary.X1.Meza@kp.org

Curriculum vitae (CV)

Morgan Justice, MA

Collaborative Scientist
Morgan.J.Fuoco@kp.org

Curriculum vitae (CV)

Theresa E. Matson, PhD, MPH

Collaborative Scientist
Tessa.E.Matson@kp.org

Curriculum vitae (CV)

Lily N. Shapiro, PhD

Collaborative Scientist
Lily.X.Shapiro@kp.org

Curriculum vitae (CV)

Affiliate researchers in mental health

Paul Crane, MD, MPH
Professor, Internal Medicine
University of Washington

Patrick Heagerty, PhD
Professor and Chair, Department of Biostatistics
University of Washington

Laura P. Richardson, MD, MPH
Adolescent Medicine
Seattle Children's Hospital
Professor, Department of Pediatrics
University of Washington

Noah R. Simon, PhD
Assistant Professor, Biostatistics
University of Washington
Principal Investigator, Therapeutics Development
Seattle Children’s Research Institute

Emily Williams, PhD, MPH
Investigator
Health Services Research & Development
VA Puget Sound Health Care System